Europium Nanoparticle-Based Lateral Flow Strip Biosensors for the Detection of Quinoxaline Antibiotics and Their Main Metabolites in Fish Feeds and Tissues-Reference-Cited by-同舟云学术

Europium Nanoparticle-Based Lateral Flow Strip Biosensors for the Detection of Quinoxaline Antibiotics and Their Main Metabolites in Fish Feeds and Tissues

Published:2024-06-04 Issue:6 Volume:14 Page:292
ISSN:2079-6374
Container-title:Biosensors
language:en
Short-container-title:Biosensors

Author:

Mei Qing¹,Ma Biao¹,Fang Yun²,Gong Yunfei¹,Li Jiali³,Zhang Mingzhou¹^ORCID

Affiliation:

1. Zhejiang Provincial Key Laboratory of Biometrology and Inspection & Quarantine, China Jiliang University, Xueyuan Street, Xiasha Higher Education Zone, Hangzhou 310018, China

2. Qianjiang Customs of the People’s Republic of China, Hangzhou 310012, China

3. Hangzhou Quickgene Sci-Tech. Co., Ltd., Hangzhou 310018, China

Abstract

Olaquindox (OLA) and quinocetone (QCT) have been prohibited in aquatic products due to their significant toxicity and side effects. In this study, rapid and visual europium nanoparticle (EuNP)-based lateral flow strip biosensors (LFSBs) were developed for the simultaneous quantitative detection of OLA, QCT, and 3-methyl-quinoxaline-2-carboxylic acid (MQCA) in fish feed and tissue. The EuNP-LFSBs enabled sensitive detection for OLA, QCT, and MQCA with a limit of detection of 0.067, 0.017, and 0.099 ng/mL (R2 ≥ 0.9776) within 10 min. The average recovery of the EuNP-LFSBs was 95.13%, and relative standard deviations were below 9.38%. The method was verified by high-performance liquid chromatography (HPLC), and the test results were consistent. Therefore, the proposed LFSBs serve as a powerful tool to monitor quinoxalines in fish feeds and their residues in fish tissues.

Funder

National Key Research and Development Program of China

Key Research and Development Program of Zhejiang Province

Public Projects of Zhejiang Province

Zhejiang Provincial Department of Agriculture and Rural Affairs Project

Publisher

MDPI AG

Link

https://www.mdpi.com/2079-6374/14/6/292/pdf

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