Hypertensive Heart Disease—The Imaging Perspective

Author:

Ismail Tevfik F.1ORCID,Frey Simon2ORCID,Kaufmann Beat A.2,Winkel David J.3ORCID,Boll Daniel T.3,Zellweger Michael J.2,Haaf Philip2ORCID

Affiliation:

1. King’s College London & Cardiology Department, School of Biomedical Engineering and Imaging Sciences, Guy’s and St Thomas’ NHS Foundation Trust, London SE1 7EH, UK

2. Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Petersgraben 4, CH-4031 Basel, Switzerland

3. Department of Radiology, University Hospital Basel, University of Basel, CH-4031 Basel, Switzerland

Abstract

Hypertensive heart disease (HHD) develops in response to the chronic exposure of the left ventricle and left atrium to elevated systemic blood pressure. Left ventricular structural changes include hypertrophy and interstitial fibrosis that in turn lead to functional changes including diastolic dysfunction and impaired left atrial and LV mechanical function. Ultimately, these changes can lead to heart failure with a preserved (HFpEF) or reduced (HFrEF) ejection fraction. This review will outline the clinical evaluation of a patient with hypertension and/or suspected HHD, with a particular emphasis on the role and recent advances of multimodality imaging in both diagnosis and differential diagnosis.

Publisher

MDPI AG

Subject

General Medicine

Reference83 articles.

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