Effect of Aging on Intraventricular Kinetic Energy and Energy Dissipation

Author:

Mele Donato1ORCID,Beccari Riccardo1ORCID,Pedrizzetti Gianni2ORCID

Affiliation:

1. Department of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35128 Padova, Italy

2. Department of Engineering and Architecture, University of Trieste, 34127 Trieste, Italy

Abstract

In recent years, analysis of kinetic energy (KE) and the rate of kinetic energy dissipation (KED) or energy loss (EL) within the cardiac chambers, obtained by cardiac imaging techniques, has gained increasing attention. Thus, there is a need to clarify the effect of physiological variables, specifically aging, on these energetic measures. To elucidate this aspect, we reviewed the literature on this topic. Overall, cardiac magnetic resonance and echocardiographic studies published so far indicate that aging affects the energetics of left and right intraventricular blood flow, although not all energy measures during the cardiac cycle seem to be affected by age in the same way. Current studies, however, have limitations. Additional large, multicenter investigations are needed to test the effect of physiological variables on intraventricular KE and KED/EL measures.

Publisher

MDPI AG

Subject

Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics

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