Evaluation of Vaccine Immunogenicity—Correlates to Real-World Protection: Influenza-Reference-Cited by-同舟云学术

Evaluation of Vaccine Immunogenicity—Correlates to Real-World Protection: Influenza

Published:2024-03-12 Issue:3 Volume:16 Page:441
ISSN:1999-4915
Container-title:Viruses
language:en
Short-container-title:Viruses

Author:

Laszlofy Csaba¹^ORCID,Fazekas Gyorgy²,Barath Zoltan¹,Vajo Zoltan³^ORCID

Affiliation:

1. Department of Prosthodontics, Faculty of Dentistry, University of Szeged, 6720 Szeged, Hungary

2. Fluart Innovations Ltd., 2097 Pilisborosjeno, Hungary

3. Department of Family Medicine, Semmelweis University Medical School, 1085 Budapest, Hungary

Abstract

Recent events highlighted that, despite decades of studying vaccine immunogenicity and efforts toward finding correlates of protection, evaluating real-world vaccine efficacy as well as establishing meaningful licensing criteria still represents a significant challenge. In this paper, we review all aspects of influenza vaccine immunogenicity, including animal and human challenge studies, humoral and cellular immunity parameters, and their potential correlation with real-life protection from disease.

Publisher

MDPI AG

Link

https://www.mdpi.com/1999-4915/16/3/441/pdf

Reference51 articles.

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