The Effect of Dietary Supplementation with Probiotic and Postbiotic Yeast Products on Ewes Milk Performance and Immune Oxidative Status
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Published:2023-11-25
Issue:12
Volume:9
Page:1139
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ISSN:2309-608X
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Container-title:Journal of Fungi
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language:en
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Short-container-title:JoF
Author:
Christodoulou Christos1ORCID, Skourtis Alexis1, Kyriakaki Panagiota1ORCID, Satolias Fotis Fokion1, Karabinas Dimitris1, Briche Maxime2, Salah Nizar2, Zervas George1, Mavrommatis Alexandros1ORCID, Tsiplakou Eleni1ORCID
Affiliation:
1. Laboratory of Nutritional Physiology and Feeding, Department of Animal Science, School of Animal Biosciences, Agricultural University of Athens, Iera Odos 75, GR-11855 Athens, Greece 2. Phileo by Lesaffre, 59700 Marcq en Baroeul, Nord, France
Abstract
The administration of yeast products as feed additives has been proven to beneficially affect animal productivity through energy, oxidative, and immune status improvement. This study evaluated a combination of Saccharomyces cerevisiae live yeast (LY) with yeast postbiotics (rich in mannan-oligosaccharides (MOS) and beta-glucans) and selenium (Se)-enriched yeast on ewes’ milk performance and milk quality, energy and oxidative status, and gene expression related to their immune system during the peripartum period. Ewes were fed a basal diet (BD; F:C = 58:42 prepartum and 41:59 postpartum) including inorganic Se (CON; n = 27), the BD supplemented with a LY product, and inorganic Se (AC; n = 29), as well as the combination of the LY, a product of yeast fraction rich in MOS and beta-glucans, and organic-Se-enriched yeast (ACMAN; n = 26) from 6 weeks prepartum to 6 weeks postpartum. The β-hydroxybutyric acid concentration in the blood of AC and ACMAN ewes was lower (compared to the CON) in both pre- and postpartum periods (p < 0.010). Postpartum, milk yield was increased in the AC and ACMAN Lacaune ewes (p = 0.001). In addition, the activity of superoxide dismutase (p = 0.037) and total antioxidant capacity (p = 0.034) measured via the 2,2-Azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) method was increased in the blood plasma of the ACMAN postpartum. Higher ABTS values were also found (p = 0.021), while protein carbonyls were reduced (p = 0.023) in the milk of the treated groups. The relative transcript levels of CCL5 and IL6 were downregulated in the monocytes (p = 0.007 and p = 0.026 respectively), and those of NFKB were downregulated in the neutrophils of the ACMAN-fed ewes postpartum (p = 0.020). The dietary supplementation of ewes with yeast postbiotics rich in MOS and beta-glucans, and organic Se, improved energy status, milk yield and some milk constituents, and oxidative status, with simultaneous suppression of mRNA levels of proinflammatory genes during the peripartum period.
Funder
Phileo by Lesaffre, Marcq en Baroeul, 59700 Nord, France and Karabinas S.A
Subject
Plant Science,Ecology, Evolution, Behavior and Systematics,Microbiology (medical)
Reference69 articles.
1. Nutritional strategies in ruminants: A lifetime approach;McGrath;Res. Vet. Sci.,2018 2. Invited review: Inflammation during the transition to lactation: New adventures with an old flame;Bradford;J. Dairy Sci.,2015 3. Abuelo, A., Hernández, J., Benedito, J.L., and Castillo, C. (2019). Redox biology in transition periods of dairy cattle: Role in the health of periparturient and neonatal animals. Antioxidants, 8. 4. Metabolic profile and oxidative status in goats during the peripartum period;Pietro;Aust. J. Exp. Agric.,2008 5. Duniere, L., Esparteiro, D., Lebbaoui, Y., Ruiz, P., Bernard, M., Thomas, A., Durand, D., Forano, E., and Chaucheyras-Durand, F. (2021). Changes in Digestive Microbiota, Rumen Fermentations and Oxidative Stress around Parturition Are Alleviated by Live Yeast Feed Supplementation to Gestating Ewes. J. Fungi, 7.
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