Re-Do Plastic Reconstruction for Locally Advanced and Recurrent Colorectal Cancer Following a beyond Total Mesorectal Excision (TME) Operation—Key Considerations

Author:

Giannas Emmanuel12,Kavallieros Konstantinos12ORCID,Nanidis Theodoros3,Giannas John45,Tekkis Paris126,Kontovounisios Christos1267ORCID

Affiliation:

1. Department of Surgery and Cancer, Imperial College London, London SW7 2BX, UK

2. Department of General Surgery, Chelsea and Westminster Hospital, London SW10 9NH, UK

3. Department of Plastic Surgery, The Royal Marsden Hospital, London SW3 6JJ, UK

4. Department of Plastic and Reconstructive Surgery, Euroclinic, 115 21 Athens, Greece

5. Department of Plastic and Reconstructive Surgery, The London Welbeck Hospital, London W1G 83N, UK

6. Department of Surgery, The Royal Marsden Hospital, London SE3 6JJ, UK

7. 2nd Surgical Department Evaggelismos, Athens General Hospital, 115 21 Athens, Greece

Abstract

Innovation in surgery and pelvic oncology have redefined the boundaries of pelvic exenteration for CRC. However, surgical approaches and outcomes following repeat exenteration and reconstruction are not well described. The resulting defect from a second beyond Total Mesorectal Excision (TME) presents a challenge to the reconstructive surgeon. The aim of this study was to explore reconstructive options for patients undergoing repeat beyond TME for recurrent CRC following previous beyond TME and regional reconstruction. MEDLINE and Embase were searched for relevant articles, yielding 2353 studies. However, following full text review and the application of the inclusion criteria, all the studies were excluded. This study demonstrated the lack of reporting on re-do reconstruction techniques following repeat exenteration for recurrent CRC. Based on this finding, we conducted a point-by-point discussion of certain key aspects that should be taken into consideration when approaching this patient cohort.

Publisher

MDPI AG

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