Intraoperative Predictors and Proposal for a Novel Prognostic Risk Score for In-Hospital Mortality after Open Repair of Ruptured Abdominal Aortic Aneurysms (SPARTAN Score)

Author:

Berchiolli Raffaella1,Troisi Nicola1ORCID,Bertagna Giulia1ORCID,D’Oria Mario2ORCID,Mezzetto Luca3ORCID,Malquori Vittorio1,Artini Valerio1,Motta Duilio1,Grosso Lorenzo3ORCID,Grando Beatrice2,Badalamenti Giovanni2,Calvagna Cristiano2,Mastrorilli Davide3,Veraldi Gian Franco3,Adami Daniele1,Lepidi Sandro2

Affiliation:

1. Vascular Surgery Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy

2. Vascular and Endovascular Surgery Unit, Cardio-Thoraco-Vascular Department, Azienda Sanitaria Universitaria Giuliano Isontina, 34148 Trieste, Italy

3. Unit of Vascular Surgery, Department of Cardio-Thoraco-Vascular Surgery, University Hospital and Trust of Verona, University of Verona School of Medicine, 37134 Verona, Italy

Abstract

(1) Background: Several mortality risk scores have been developed to predict mortality in ruptured abdominal aortic aneurysms (rAAAs), but none focused on intraoperative factors. The aim of this study is to identify intraoperative variables affecting in-hospital mortality after open repair and develop a novel prognostic risk score. (2) Methods: The analysis of a retrospectively maintained dataset identified patients who underwent open repair for rAAA from January 2007 to October 2023 in three Italian tertiary referral centers. Multinomial logistic regression was used to calculate the association between intraoperative variables and perioperative mortality. Independent intraoperative factors were used to create a prognostic score. (3) Results: In total, 316 patients with a mean age of 77.3 (SD ± 8.5) were included. In-hospital mortality rate was 30.7%. Hemoperitoneum (p < 0.001), suprarenal clamping (p = 0.001), and operation times of >240 min (p = 0.008) were negative predictors of perioperative mortality, while the patency of at least one hypogastric artery had a protective role (p = 0.008). Numerical values were assigned to each variable based on the respective odds ratio to create a risk stratification for in-hospital mortality. (4) Conclusions: rAAA represents a major cause of mortality. Intraoperative variables are essential to estimate patients’ risk in surgically treated patients. A prognostic risk score based on these factors alone may be useful to predict in-hospital mortality after open repair.

Publisher

MDPI AG

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