A Short Fully Covered Self-Expandable Metal Stent for Management of Benign Biliary Stricture Not Caused by Living-Donor Liver Transplantation

Author:

Lee See-Young1ORCID,Jang Sung-Ill1ORCID,Chung Moon-Jae1ORCID,Cho Jae-Hee1ORCID,Do Min-Young1,Lee Hye-Sun2ORCID,Yang Juyeon2ORCID,Lee Dong-Ki1

Affiliation:

1. Department of Internal Medicine, Institute of Gastroenterology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea

2. Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul 03722, Republic of Korea

Abstract

Background: This study evaluated the effectiveness of short fully covered self-expanding metal stents (FCSEMS) with an anti-migration design in treating benign biliary strictures (BBS) not related to living donor liver transplantation (LDLT). Methods: A retrospective analysis was conducted on 75 patients who underwent FCSEMS insertion for BBS management. Stents were initially kept for 3 months and exchanged every 3 months until stricture resolution. Adverse events and stricture recurrence after FCSEMS removal were assessed during follow-up. Results: The study outcomes were technical success, stenosis resolution, and treatment failure. Technical success was 100%, with stricture resolution in 99% of patients. The mean onset time of BBS post-surgery was 4.4 years, with an average stent indwelling period of 5.5 months. Stricture recurrence occurred in 20% of patients, mostly approximately 18.8 months after stent removal. Early cholangitis and stent migration were noted in 3% and 4% of patients, respectively. Conclusions: This study concludes that short FCSEMS demonstrate high efficacy in the treatment of non-LDLT-related BBS, with a low incidence of interventions and complications. Although this is a single-center, retrospective study with a limited sample size, the findings provide preliminary evidence supporting the use of short FCSEMS as a primary treatment modality for BBS. To substantiate these findings, further research involving multicenter studies is recommended to provide additional validation and a broader perspective.

Funder

the Korean Gastrointestinal Endoscopy Research Foundation’s Pharmaceutical Research Fund

Gangnam Severance Hospital, Yonsei University College of Medicine

the Yonsei University College of Medicine

Publisher

MDPI AG

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