Update on Diagnosis and Treatment of Uveitic Glaucoma

Author:

Halkiadakis Ioannis1ORCID,Konstantopoulou Kalliroi1,Tzimis Vasilios1,Papadopoulos Nikolaos1,Chatzistefanou Klio2,Markomichelakis Nikolaos N.3

Affiliation:

1. Ophthalmiatrion Athinon, Athens Eye Hospital, 10672 Athens, Greece

2. First Department of Ophthalmology, National and Kapodistrian University of Athens School of Medicine, Athens General Hospital “G. Gennimatas”, 11527 Athenbs, Greece

3. Ocular Inflammation Institute of Athens, Sarantaporou 7 Agios Stefanos, 14565 Athens, Greece

Abstract

Glaucoma is a common and potentially blinding complication of uveitis. Many mechanisms are involved alone or in combination in the pathogenesis of uveitic glaucoma (UG). In terms of diagnostic evaluation, the effects of inflammatory activity in the retinal nerve fiber layer may be a source of bias in the interpretation of optical coherence tomography measurements. For the successful treatment of UG, the control of intraocular inflammation specific to the cause or anti-inflammatory treatment, combined with IOP management, is mandatory. The early institution of specific treatment improves the prognosis of UG associated with CMV. The young age of UG patients along with increased failure rates of glaucoma surgery in this group of patients warrants a stepwise approach. Conservative and conjunctival sparing surgical approaches should be adopted. Minimally invasive surgical approaches were proved to be effective and are increasingly being used in the management of UG along with the traditionally used techniques of trabeculectomy or tubes. This review aims to summarize the progress that recently occurred in the diagnosis and treatment of UG.

Publisher

MDPI AG

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