An Investigation of the Relationship between Henoch-Schönlein Purpura and Viral Infection in Korea Using the Health Insurance Database

Author:

Park So Hyeon1,Jo Su Min1,Kim Sang Won2ORCID,Lee Jae Min3ORCID,Baek Hee Sun3

Affiliation:

1. Department of Medicine, College of Medicine, Yeungnam University, Daegu 42415, Republic of Korea

2. Medical Research Center, College of Medicine, Yeungnam University, Daegu 42415, Republic of Korea

3. Department of Pediatrics, College of Medicine, Yeungnam University, Daegu 42415, Republic of Korea

Abstract

(1) Background: This study investigated the epidemiology and viral connections of Henoch–Schönlein purpura (HSP) using information from the Korea Disease Control and Prevention Agency and the Health Insurance Review and Assessment database. (2) Method: Between 2016 and 2019, a total of 25,443 patients with HSP were identified, with 51.3% of patients under the age of 20 years and the highest incidence in March. (3) Results: The autoregressive integrated moving average model and Granger causality test were used to analyze the association between the virus positivity detection rate and HSP incidence. (4) Conclusions: The incidence of HSP was associated with rotavirus, bocavirus, parainfluenza virus, and respiratory syncytial virus in individuals under 20 years of age, whereas adenovirus, respiratory syncytial virus, and norovirus were associated with individuals above that age.

Funder

2021 Yeungnam University Research Grant

Publisher

MDPI AG

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