Potassium Ferrite for Biomedical Applications
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Published:2023-05-22
Issue:10
Volume:16
Page:3880
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ISSN:1996-1944
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Container-title:Materials
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language:en
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Short-container-title:Materials
Author:
Carvalho João P. F.1ORCID, Vieira Tânia2, Silva Jorge Carvalho2ORCID, Soares Paula I. P.3ORCID, Ferreira Nuno M.1ORCID, Amorim Carlos O.4ORCID, Teixeira Sílvia Soreto1ORCID, Graça Manuel P. F.1ORCID
Affiliation:
1. i3N and Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal 2. i3N/CENIMAT, Physics Department, NOVA School of Science and Technology, Campus de Caparica, NOVA University Lisbon, 2829-516 Caparica, Portugal 3. i3N/CENIMAT, Materials Science Department, NOVA School of Science and Technology, Campus de Caparica, NOVA University Lisbon, 2829-516 Caparica, Portugal 4. CICECO-Aveiro Institute of Materials and Department of Physics, University of Aveiro, 3810-193 Aveiro, Portugal
Abstract
Ferrites have been widely studied for their use in the biomedical area, mostly due to their magnetic properties, which gives them the potential to be used in diagnostics, drug delivery, and in treatment with magnetic hyperthermia, for example. In this work, KFeO2 particles were synthesized with a proteic sol-gel method using powdered coconut water as a precursor; this method is based on the principles of green chemistry. To improve its properties, the base powder obtained was subjected to multiple heat treatments at temperatures between 350 and 1300 °C. The samples obtained underwent structural, morphological, biocompatibility, and magnetic characterization. The results show that upon raising the heat treatment temperature, not only is the wanted phase detected, but also the secondary phases. To overcome these secondary phases, several different heat treatments were carried out. Using scanning electron microscopy, grains in the micrometric range were observed. Saturation magnetizations between 15.5 and 24.1 emu/g were observed for the samples containing KFeO2 with an applied field of 50 kOe at 300 K. From cellular compatibility (cytotoxicity) assays, for concentrations up to 5 mg/mL, only the samples treated at 350 °C were cytotoxic. However, the samples containing KFeO2, while being biocompatible, had low specific absorption rates (1.55–5.76 W/g).
Subject
General Materials Science
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