Research Progress on the Role of M6A in Regulating Economic Traits in Livestock-Reference-Cited by-同舟云学术

Research Progress on the Role of M6A in Regulating Economic Traits in Livestock

Published:2024-07-31 Issue:15 Volume:25 Page:8365
ISSN:1422-0067
Container-title:International Journal of Molecular Sciences
language:en
Short-container-title:IJMS

Author:

Ren Tuanhui¹^ORCID,Xu Meng¹,Du Xinyu¹,Wang Yanxi¹,Loor Juan J.²^ORCID,Lei Lin¹^ORCID,Gao Wenwen¹,Du Xiliang¹,Song Yuxiang¹,Liu Guowen¹,Li Xinwei¹

Affiliation:

1. State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun 130062, China

2. Mammalian NutriPhysioGenomics, Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana, IL 61801, USA

Abstract

Reversible regulation of N6-methyladenosine (m6A) methylation of eukaryotic RNA via methyltransferases is an important epigenetic event affecting RNA metabolism. As such, m6A methylation plays crucial roles in regulating animal growth, development, reproduction, and disease progression. Herein, we review the latest research advancements in m6A methylation modifications and discuss regulatory aspects in the context of growth, development, and reproductive traits of livestock. New insights are highlighted and perspectives for the study of m6A methylation modifications in shaping economically important traits are discussed.

Funder

Jilin Province Young and Middle-aged Outstanding Talent in Science and Technology Innovation and Entrepreneurship

Fundamental Research Funds

Publisher

MDPI AG

Link

https://www.mdpi.com/1422-0067/25/15/8365/pdf

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