Craniofacial Development Is Fine-Tuned by Sox2-Reference-Cited by-同舟云学术

Craniofacial Development Is Fine-Tuned by Sox2

Published:2023-01-31 Issue:2 Volume:14 Page:380
ISSN:2073-4425
Container-title:Genes
language:en
Short-container-title:Genes

Author:

Mandalos Nikolaos Panagiotis¹²,Dimou Aikaterini¹³,Gavala Maria Angeliki¹⁴,Lambraki Efstathia¹⁵,Remboutsika Eumorphia¹⁶^ORCID

Affiliation:

1. University Research Institute of Maternal and Child Health & Precision Medicine, School of Medicine, National and Kapoditrian University of Athens, 115 27 Athens, Greece

2. National Cancer Institute, Frederick, MD 21702, USA

3. Center for Translational Medicine and the Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA

4. National Technical University of Athens, 157 80 Athens, Greece

5. Polytechnic School, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece

6. Thrivus Institute for Biomedical Science and Technology, Constellations Ave, Accra GT-336-4330, Ghana

Abstract

The precise control of neural crest stem cell delamination, migration and differentiation ensures proper craniofacial and head development. Sox2 shapes the ontogeny of the cranial neural crest to ensure precision of the cell flow in the developing head. Here, we review how Sox2 orchestrates signals that control these complex developmental processes.

Publisher

MDPI AG

Subject

Genetics (clinical),Genetics

Link

https://www.mdpi.com/2073-4425/14/2/380/pdf

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