Genome-Wide Association Study of Phenolic Content and Antioxidant Properties in Eggplant Germplasm

Author:

Ro Nayoung1,Haile Mesfin1ORCID,Ko Ho-Cheol1,Cho Gyu-Taek1,Lee Jungro1,Kim Bichsaem1,Lee Sookyeong1ORCID,Kim Seong-Hoon1ORCID

Affiliation:

1. National Agrobiodiversity Center, National Institute of Agricultural Sciences, Rural Development Administration, Jeonju 54874, Republic of Korea

Abstract

The phenolic compounds in eggplant offer potential natural antioxidants for improved health. A large number of samples were examined in order to find eggplant germplasm with a high potential for health promotion. A genome-wide association study (GWAS) was conducted to identify single nucleotide polymorphisms (SNPs) associated with variations in total phenolic content (TPC) and antioxidant activity in eggplants, including ABTS (2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)) scavenging activity and ferric reducing antioxidant power (FRAP). TPC values varied from 14.19 to 842.90 mg gallic acid equivalent (GAE)/100 g of dry weight of eggplant fruit powder. TPC showed a strong positive correlation with both FRAP and ABTS (r = 0.89 *** and 0.77 ***, respectively). The GWAS identified 20 SNPs that were significantly associated out of 29,183 SNPs. Out of the 20 significant SNPs, 11 showed associations with TPC, 4 with ABTS activity, and 5 with FRAP. Among the SNPs associated with TPC, one SNP was found on each of Chromosomes 3, 4, 7, and 12. In contrast, Chromosome 5 comprised two SNPs associated to TPC. Furthermore, the gene encoding IRX12 laccase-4 on Chromosome 10 was found to contain five SNPs associated with TPC. Four significantly linked SNPs on Chromosomes 1 (1 SNP), 4 (2 SNPs), and 10 (1 SNP) were found to be related to ABTS activity. The identified SNPs will be further examined as markers for selecting desirable eggplant varieties and exploring the links between candidate genes, phenolic content, and antioxidant activity. The findings of this study could assist in further study and the development of eggplants with improved health advantages through targeted breeding.

Funder

National Institute of Agricultural Sciences

Publisher

MDPI AG

Subject

Genetics (clinical),Genetics

Reference75 articles.

1. Eggplant Origins: Out of Africa, into the Orient;Weese;Taxon,2010

2. FAOSTAT (2023, April 19). FAOSTAT Statistical Database 2019. Available online: https://www.fao.org/faostat/en/#data/QCL/visualize.

3. Health Benefits and Bioactive Compounds of Eggplant;Food Chem.,2018

4. Horincar, G., Enachi, E., Barbu, V., Andronoiu, D.G., Râpeanu, G., Stănciuc, N., and Aprodu, I. (2020). Value-Added Pastry Cream Enriched with Microencapsulated Bioactive Compounds from Eggplant (Solanum melongena L.) Peel. Antioxidants, 9.

5. Nutritional Content and Health Benefits of Bangladeshi Eggplant Cultivars;Quamruzzaman;Eur. J. Agric. Food Sci.,2020

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