Abstract
Osteosarcoma (OS) is a highly malignant tumor occurring in bone tissue with a high propensity to metastasize, and its underlying mechanisms remain largely elusive. The OS prognosis is poor, and improving the survival of OS patients remains a challenge. Current treatment methods such as surgical approaches, chemotherapeutic drugs, and immunotherapeutic drugs remain ineffective. As research progresses, targeted therapy is gradually becoming irreplaceable. In this review, several treatment modalities for osteosarcoma, such as surgery, chemotherapy, and immunotherapy, are briefly described, followed by a discussion of targeted therapy, the important targets, and new technologies for osteosarcoma treatment.
Funder
Shandong Province Natural Science Foundation of China
Support Program for Youth Innovation Technology in Colleges and Universities of Shandong Province of China
Shandong Province Chinese medicine science and technology developmental project
Shandong medical and health science and technology development plan project
Gillian Reny Stepping Strong Center for Trauma Innovation, the Osteobiology Research Fund, and the Osteobiology Training Fund
Cited by
15 articles.
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