Considerations for the Use of Photobiomodulation in the Treatment of Retinal Diseases

Author:

Zhang Chun-XiaORCID,Lou Yan,Chi JingORCID,Bao Xiao-Li,Fan Bin,Li Guang-YuORCID

Abstract

Photobiomodulation (PBM) refers to the beneficial effect produced from low-energy light irradiation on target cells or tissues. Increasing evidence in the literature suggests that PBM plays a positive role in the treatment of retinal diseases. However, there is great variation in the light sources and illumination parameters used in different studies, resulting in significantly different conclusions regarding PBM’s therapeutic effects. In addition, the mechanism by which PBM improves retinal function has not been fully elucidated. In this study, we conducted a narrative review of the published literature on PBM for treating retinal diseases and summarized the key illumination parameters used in PBM. Furthermore, we explored the potential molecular mechanisms of PBM at the retinal cellular level with the goal of providing evidence for the improved utilization of PBM in the treatment of retinal diseases.

Funder

Joint Project Between Suzhou Xuanjia Photoelectric Technology Co., Ltd.

Natural Science Foundation of Jilin Province

Publisher

MDPI AG

Subject

Molecular Biology,Biochemistry

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