Abstract
Photobiomodulation (PBM) refers to the beneficial effect produced from low-energy light irradiation on target cells or tissues. Increasing evidence in the literature suggests that PBM plays a positive role in the treatment of retinal diseases. However, there is great variation in the light sources and illumination parameters used in different studies, resulting in significantly different conclusions regarding PBM’s therapeutic effects. In addition, the mechanism by which PBM improves retinal function has not been fully elucidated. In this study, we conducted a narrative review of the published literature on PBM for treating retinal diseases and summarized the key illumination parameters used in PBM. Furthermore, we explored the potential molecular mechanisms of PBM at the retinal cellular level with the goal of providing evidence for the improved utilization of PBM in the treatment of retinal diseases.
Funder
Joint Project Between Suzhou Xuanjia Photoelectric Technology Co., Ltd.
Natural Science Foundation of Jilin Province
Subject
Molecular Biology,Biochemistry
Reference73 articles.
1. Mechanisms and Mitochondrial Redox Signaling in Photobiomodulation;Hamblin;Photochem. Photobiol.,2018
2. Photobiomodulation reduces drusen volume and improves visual acuity and contrast sensitivity in dry age-related macular degeneration;Merry;Acta Ophthalmol.,2017
3. Preclinical and clinical studies of photobiomodulation therapy for macular oedema;Shen;Diabetologia,2020
4. Natoli, R., Valter, K., Barbosa, M., Dahlstrom, J., Rutar, M., Kent, A., and Provis, J. (2013). 670 nm photobiomodulation as a novel protection against retinopathy of prematurity: Evidence from oxygen induced retinopathy models. PLoS ONE, 8.
5. Therapeutic photobiomodulation for methanol-induced retinal toxicity;Eells;Proc. Natl. Acad. Sci. USA,2003
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献