Affiliation:
1. Institute of Forensic Sciences, Turkish National Police Academy, 06834 Ankara, Turkey
2. Graduate School of Natural and Applied Sciences, Istanbul Ticaret University, 34840 Istanbul, Turkey
Abstract
Poly-ε-caprolactone (PCL) is a biodegradable aliphatic polyester that can be used in the field of biomaterials. Electrospinning is the name given to the process of producing micro and nanoscale fibers using electrostatically charged polymeric solutions under certain conditions. Almost all synthetic and naturally occurring polymers can undergo electrospinning using suitable solvents or mixtures prepared in certain proportions. In this study, silica aerogels were obtained by the sol-gel method. PCL-silica aerogel fibers were synthesized by adding 0.5, 1, 2, and 4% ratios in the PCL solution. Blood contact analysis was performed on the produced fibers with UV-VIS. According to the results obtained, 0.5, 1, 2, and 4% nano-silver were added to the fiber-containing 4% aerogel. Then, SEM-EDS and FTIR analyses were performed on all fibers produced. Antimicrobial tests were performed on fibers containing nano-silver. As a result, high-performance blood coagulation fibers were developed using PCL with aerogel, and an antimicrobial effect was achieved with nano-silver particles. It is thought that the designed surface will be preferred in wound dressing and biomaterial in tissue engineering, as it provides a high amount of cell adhesion with a small amount of blood and contains antimicrobial properties.
Funder
Istanbul Ticaret University
Subject
Polymers and Plastics,General Chemistry
Reference46 articles.
1. Characterization of the biocompatibility and mechanical properties of polyurea organic aerogels with the vascular system: Potential as a blood implantable material;Yin;Int. J. Polym. Mater.,2013
2. Synthesis and properties of chitosan–silica hybrid aerogels;Ayers;J. Non-Cryst. Solids,2001
3. A novel method for preparing a protein-encapsulated aerogel: Using a red fluorescent protein as a model;Li;Acta Biomater.,2008
4. Bioactivity of wollastonite/aerogels composites obtained from a TEOS–MTES matrix;Morales;J. Mater. Sci. Mater. Med.,2008
5. Biocompatibility of surfactant-templated polyurea–nano encapsulated macroporous silica aerogels with plasma platelets and endothelial cells;Yin;J. Biomed. Mater. Res. Part A Off. J. Soc. Biomater. Jpn. Soc. Biomater. Aust. Soc. Biomater. Korean Soc. Biomater.,2010
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