Structures, Properties, and Bioengineering Applications of Alginates and Hyaluronic Acid

Author:

Zhang Shuping1,Dong Jiayu1,Pan Renxue1,Xu Zhenyang1,Li Mengyuan1,Zang Rui1

Affiliation:

1. School of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai 200093, China

Abstract

In recent years, polymeric materials have been used in a wide range of applications in a variety of fields. In particular, in the field of bioengineering, the use of natural biomaterials offers a possible new avenue for the development of products with better biocompatibility, biodegradability, and non-toxicity. This paper reviews the structural and physicochemical properties of alginate and hyaluronic acid, as well as the applications of the modified cross-linked derivatives in tissue engineering and drug delivery. This paper summarizes the application of alginate and hyaluronic acid in bone tissue engineering, wound dressings, and drug carriers. We provide some ideas on how to replace or combine alginate-based composites with hyaluronic-acid-based composites in tissue engineering and drug delivery to achieve better eco-economic value.

Funder

Medical-Industrial Crossover Project of High-level University Construction

Ministry of Agriculture and Rural Affairs Key Laboratory

civil-military integration projects of High-level university

Publisher

MDPI AG

Subject

Polymers and Plastics,General Chemistry

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