The Effects of Body Cold Exposure (Cryolipolysis) on Fat Mass and Plasma Cholesterol

Author:

Lopes-Martins Rodrigo Alvaro Brandão12ORCID,Barbosa Ludymilla Vicente3,Sousa Mirian Martins Barbosa1ORCID,Lobo Anna Beatriz1,Santos Elize Leonice da Rocha3,Sá Filho Alberto Souza de4ORCID,Souza Matheus Bernardes1,Jaime Jivago Carneiro1,Silva Constanza Thaise Xavier da1,Ruiz-Silva Carlos2,Leonardo Patrícia Sardinha3

Affiliation:

1. Laboratory of Biophotonics and Experimental Therapeutics (LABITEX), Universidade Evangélica de Goiás, Av. Universitária Km 3,5, Anápolis 75083-515, Brazil

2. Programa de Pós-Graduação em Bioengenharia, Universidade Brasil, Av. Carolina Fonseca 236, Itaquera, São Paulo 08230-030, Brazil

3. Laboratory of Health Technologies (LATES), Universidade Evangélica de Goiás, Av. Universitária Km 3,5, Anápolis 75083-515, Brazil

4. Department of Physical Education, Evangelical University of Goiás (UniEVANGÉLICA), Anápolis 75083-515, Brazil

Abstract

Introduction: This study investigates the impact of cryolipolysis on reducing localized fat and altering plasma lipid profiles in 30 overweight and obese women. Conducted at the Health Technology Laboratory of the Evangelical University of Goiás, this clinical research adhered to stringent ethical guidelines. Methods: Participants underwent three cryolipolysis sessions, with comprehensive assessments of body composition and plasma lipids performed pre- and post-intervention. Results: Significant findings include a reduction in abdominal fat mass by an average of 4.1 kg and a decrease in BMI by 0.7 points (p < 0.05). Notably, total cholesterol levels decreased by an average of 15.7 mg/dL, and LDL cholesterol saw a reduction of 10.2 mg/dL (p < 0.01), with no significant changes in HDL cholesterol or triglyceride levels. These results suggest that cryolipolysis, in conjunction with standardized dietary control, offers a non-invasive alternative to surgical fat reduction, potentially mitigating cardiovascular risks associated with obesity. Conclusions: The study confirms the efficacy of cryolipolysis in targeted fat reduction and underscores its role in improving key cardiovascular risk factors. These findings warrant further exploration into the long-term benefits of cryolipolysis in metabolic health management and not only for aesthetic treatments.

Funder

Goiás Research Foundation

National Council for Scientific and Technological Development (CNPq)—Rodrigo Alvaro B. Lopes-Martins

Publisher

MDPI AG

Reference34 articles.

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2. Hales, C.M., Carroll, M.D., Fryar, C.D., and Ogden, C.L. (2020, November 20). Prevalence of Obesity and Severe Obesity Among Adults: United States, 2017–2018. NCHS Data Brief No. 360, Available online: https://www.cdc.gov/nchs/products/databriefs/db360.htm.

3. Nearly a decade on—Trends, risk factors and policy implications in global obesity;Malik;Nat. Rev. Endocrinol.,2020

4. Heart Disease and Stroke Statistics-2020 Update: A Report From the American Heart Association;Virani;Circulation,2020

5. Sex-specific differences in hypertension and associated cardiovascular disease;Colafella;Nat. Rev. Nephrol.,2018

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