Author:
Du Li-Hua,Xue Miao,Yang Meng-Jie,Pan Yue,Zheng Ling-Yan,Ou Zhi-Min,Luo Xi-Ping
Abstract
An efficient method for the preparation of β-amino alcohols catalyzed by lipase TL IM from Thermomyces lanuginosus in a continuous-flow reactor was developed. The eco-friendly biocatalyst combined with continuous-flow reaction technology displayed high efficiency in the synthesis of β-amino alcohols. The benign reaction conditions (35 °C) and short residence time (20 min), together with the use of low cost and readily available starting materials, make this synthetic approach a promising alternative to current β-amino alcohol synthesis.
Subject
Physical and Theoretical Chemistry,Catalysis
Cited by
7 articles.
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