The Association of Asthma with Anxiety, Depression, and Mild Cognitive Impairment among Middle-Aged and Elderly Individuals in Saudi Arabia
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Published:2023-10-16
Issue:10
Volume:13
Page:842
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ISSN:2076-328X
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Container-title:Behavioral Sciences
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language:en
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Short-container-title:Behavioral Sciences
Author:
Abuaish Sameera1ORCID, Eltayeb Huda1ORCID, Bepari Asmatanzeem1ORCID, Hussain Syed Arif2, Alqahtani Raneem Saad1, Alshahrani Waad Saeed1, Alqahtani Amjad Hayf1, Almegbil Nada Saad1, Alzahrani Wafa Nedal1ORCID
Affiliation:
1. Department of Basic Sciences, College of Medicine, Princess Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia 2. Respiratory Care Department, College of Applied Sciences, Almaarefa University, Riyadh 13713, Saudi Arabia
Abstract
Asthma is a common chronic inflammatory condition with increasing global prevalence. There is some evidence highlighting the effect of asthma on brain functioning. In Saudi Arabia, limited studies have examined the relationship between asthma and mental health, including cognition and mood disorders in older adults in particular. In this study, we examine the association between asthma and mental health outcomes in middle-aged and elderly individuals in Riyadh, Saudi Arabia. In a cross-sectional study, 243 subjects were recruited from outpatient clinics between 2020–2021 (non-asthmatic: n = 159, asthmatic: n = 84). The Montreal Cognitive Assessment test, the Hospital Anxiety and Depression Scale, and the Asthma Control Test were used to assess cognition, anxiety and depression, and asthma control, respectively. Logistic regression analysis while controlling for covariates revealed an association between asthma and symptoms of anxiety and depression (OR = 2.40 [95% CI: 1.07–5.35]) and mild cognitive impairment (MCI) (OR = 1.80 [95% CI: 1.00–3.24]). Poorly controlled asthma increased the odds of anxiety cases (OR = 4.88 [95% CI: 1.09–17.2]). Stratifying analysis by age intervals revealed that asthma was associated with symptoms of anxiety and depression (OR = 2.5 [95% CI: 1.00–6.08]) in middle-aged patients only, while elderly asthmatics had increased odds of having MCI (OR = 7.4 [95% CI: 2.34–23.31]). These findings highlight the possible effects of asthma and its control on mental health among middle-aged and elderly individuals in Saudi Arabia.
Funder
Princess Nourah bint Abdulrahman University Researchers Supporting
Subject
Behavioral Neuroscience,General Psychology,Genetics,Development,Ecology, Evolution, Behavior and Systematics
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