Target and Cell Therapy for Atherosclerosis and CVD

Author:

Markina Yuliya V.1ORCID,Kirichenko Tatiana V.1ORCID,Tolstik Taisiya V.1ORCID,Bogatyreva Anastasia I.1ORCID,Zotova Ulyana S.1ORCID,Cherednichenko Vadim R.1ORCID,Postnov Anton Yu.1,Markin Alexander M.12ORCID

Affiliation:

1. Petrovsky National Research Center of Surgery, Moscow 119991, Russia

2. Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University), Moscow 117198, Russia

Abstract

Cardiovascular diseases (CVD) and, in particular, atherosclerosis, remain the main cause of death in the world today. Unfortunately, in most cases, CVD therapy begins after the onset of clinical symptoms and is aimed at eliminating them. In this regard, early pathogenetic therapy for CVD remains an urgent problem in modern science and healthcare. Cell therapy, aimed at eliminating tissue damage underlying the pathogenesis of some pathologies, including CVD, by replacing it with various cells, is of the greatest interest. Currently, cell therapy is the most actively developed and potentially the most effective treatment strategy for CVD associated with atherosclerosis. However, this type of therapy has some limitations. In this review, we have tried to summarize the main targets of cell therapy for CVD and atherosclerosis in particular based on the analysis using the PubMed and Scopus databases up to May 2023.

Funder

The Ministry of Science and Higher Education of the Russian Federation - the state task of Petrovsky National Research Centre of Surgery

Publisher

MDPI AG

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Nanotechnology-based non-viral vectors for gene delivery in cardiovascular diseases;Frontiers in Bioengineering and Biotechnology;2024-01-18

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