Microbiota and Glucidic Metabolism: A Link with Multiple Aspects and Perspectives

Author:

Ciarambino Tiziana1ORCID,Crispino Pietro2,Leto Gaetano3,Minervini Giovanni4,Para Ombretta5,Giordano Mauro6ORCID

Affiliation:

1. Internal Medicine Department, Hospital of Marcianise, ASL Caserta, 81037 Caserta, Italy

2. Internal Medicine Department, Hospital of Latina, ASL Latina, 04100 Latina, Italy

3. Department of Experimental Medicine, University La Sapienza Roma, 00185 Rome, Italy

4. Internal Medicine Department, Hospital of Lagonegro, AOR San Carlo, 85042 Lagonegro, Italy

5. Internal Emergency Department, Hospital of Careggi, University of Florence, 50121 Florence, Italy

6. Department of Medical Science, University of Campania, L. Vanvitelli, 81100 Naples, Italy

Abstract

The global prevalence of overweight and obesity has dramatically increased in the last few decades, with a significant socioeconomic burden. In this narrative review, we include clinical studies aiming to provide the necessary knowledge on the role of the gut microbiota in the development of diabetic pathology and glucose-metabolism-related disorders. In particular, the role of a certain microbial composition of the fermentative type seems to emerge without a specific link to the development in certain subjects of obesity and the chronic inflammation of the adipose tissues, which underlies the pathological development of all the diseases related to glucose metabolism and metabolic syndrome. The gut microbiota plays an important role in glucose tolerance. Conclusion. New knowledge and new information is presented on the development of individualized therapies for patients affected by all the conditions related to reduced glucose tolerance and insulin resistance.

Publisher

MDPI AG

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Gender Differences in Insulin Resistance: New Knowledge and Perspectives;Current Issues in Molecular Biology;2023-09-27

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