A Pilot Study on the Relationship between Obstructive Sleep Apnoea–Hypopnea Syndrome, Neurodevelopment, and Ricketts’ Cephalometry

Author:

Robayna Teresa I. González1ORCID,Martínez Carlos Pérez-Albacete1ORCID,Gandía Jesús M.23,Martínez Mª Dolores Austro4,Pérez Ángela Sempere5,Cascales Raúl Ferrando1ORCID

Affiliation:

1. UCAM Faculty of Dentistry, University Campus Los Jerónimos, Catholic University of Murcia, 135 Guadalupe, 30107 Murcia, Spain

2. Department of Mathematics, Physics and Technological Sciences, CEU University Cardenal Herrera, 03202 Elche, Spain

3. Statistic, Mathematics and IT Department, University Miguel Hernández, 03202 Elche, Spain

4. Dentistry Department, CEU University Cardenal Herrera, 03202 Elche, Spain

5. HLA Vistahermosa Clinic Avenida de Dénia, 103, 03015 Alicante, Spain

Abstract

Background: The aim of this research is to achieve the early detection of facial characteristics in patients diagnosed with neurodevelopmental deficits and obstructive sleep apnoea–hypopnea syndrome (OSAHS) through the analysis of the VERT index and Ricketts’ cephalometry to minimise the neurocognitive morbidity associated with these disorders. Methods: This clinical study was conducted on 44 patients aged 4 to 15 years. Participants completed an initial questionnaire about sleep disturbances, followed by a polysomnography, a radiographic study, and an oral examination. Results: The maximum variability in the data was obtained in the mandibular plane angle, where we observed that the measurement was higher in patients diagnosed with OSAHS. The relative and normalised indices of facial depth and the mandibular plane showed variations between patients with a clinical picture compatible with OSAHS and the control group without pathology. Conclusions: Our findings indicate that Ricketts’ VERT index by itself is unable to provide evidence of a diagnosis compatible with OSAHS in patients with early neurodevelopmental deficits, but, after analysing the results obtained, we observed that for the cephalometric measurements of the mandibular plane angle and facial depth relative to the patient’s age, there are sufficiently strong variations for creating a solid method of differential diagnosis, thus preventing complications at the neurocognitive level.

Publisher

MDPI AG

Reference35 articles.

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4. Management of Sleep Disorders in Children with Neurodevelopmental Disorders: A Review;Blackmer;Pharmacother. J. Hum. Pharmacol. Drug Ther.,2016

5. Obstructive sleep apnea and the prefrontal cortex: Towards a comprehensive model linking nocturnal upper airway obstruction to daytime cognitive and behavioral deficits;Beebe;J. Sleep. Res.,2002

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