Dietary Barriers Appear to Influence the Effects of a Dyadic Web-Based Lifestyle Intervention on Caloric Intake and Adiposity: A Mediation Analysis of the DUET Trial

Author:

Kaur Harleen1ORCID,Pavela Gregory2,Pekmezi Dori W.23ORCID,Rogers Laura Q.34,Cole William W.2,Parrish Kelsey B.2ORCID,Sayer R. Drew15ORCID,Wyatt Holly R.1,Demark-Wahnefried Wendy13ORCID

Affiliation:

1. Department of Nutrition Sciences, University of Alabama at Birmingham (UAB), Birmingham, AL 35294, USA

2. Department of Health Behavior, University of Alabama at Birmingham (UAB), Birmingham, AL 35294, USA

3. O’Neal Comprehensive Cancer Center at UAB, Birmingham, AL 35233, USA

4. Department of Medicine, University of Alabama at Birmingham (UAB), Birmingham, AL 35233, USA

5. Department of Family and Community Medicine, University of Alabama at Birmingham (UAB), Birmingham, AL 35205, USA

Abstract

Mechanisms that explain behavior change within web-based lifestyle interventions are not well-studied. This secondary analysis explores whether the effects of the DUET web-based lifestyle intervention on diet, physical activity, and/or adiposity are mediated through changes in self-efficacy, social support, and perceived barriers (key constructs of social cognitive theory). Data on mediators, diet quality, caloric intake, moderate-to-vigorous physical activity (MVPA), weight, and waist circumference (WC) were analyzed from 112 cancer survivors and their partners enrolled in the DUET intervention. Mediation analyses were performed using Mplus to execute regression analyses and determine associations. Mediation analyses supported an effect of the intervention on caloric intake (−3.52, 95% CI [−8.08 to −0.84]), weight (−1.60, CI [−3.84 to −0.47]), and WC (−0.83, CI [−1.77 to −0.18]), interpreting these negative associations as intervention induced reductions in dietary barriers. Higher social support was significantly and positively associated with, but not a mediator for, improvements in self-reported and accelerometry-measured MVPA (b = 0.69, CI [0.19, 1.24]) and (b = 0.55, CI [0.15, 1.00]), respectively. Self-efficacy did not appear to mediate the intervention’s effects. Findings suggest that the effects of the DUET intervention on diet and adiposity stem from reducing perceived barriers to a healthful, low-calorie diet.

Funder

American Institute for Cancer Research

American Cancer Society

National Cancer Institute

O’Neal Comprehensive Cancer Center

Cancer Prevention and Control Training Program

University of Arizona’s Comprehensive Cancer Center

Publisher

MDPI AG

Subject

Food Science,Nutrition and Dietetics

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