Standards for the Use of Enteral Nutrition in Patients with Diabetes or Stress Hyperglycaemia: Expert Consensus

Author:

Rebollo-Pérez María I.1,Florencio Ojeda Luna1ORCID,García-Luna Pedro P.23ORCID,Irles Rocamora José A.34ORCID,Olveira Gabriel5678ORCID,Lacalle Remigio Juan Ramón3,Arraiza Irigoyen Carmen9ORCID,Calañas Continente Alfonso10,Campos Martín Cristina11,Fernández Soto María Luisa1213,García Almeida José Manuel514ORCID,López María Laínez1,Losada Morell Concepción15,Luengo Pérez Luis Miguel16ORCID,Muñoz de Escalona Martínez Teodosia17,Pereira-Cunill José L.23ORCID,Vílchez-López Francisco J.18,Rabat-Restrepo Juana M.311

Affiliation:

1. Endocrinology and Nutrition Clinical Management Unit, University Hospital Juan Ramón Jiménez, 21005 Huelva, Spain

2. Regional Andalusian Health Service, Service of Endocrinology and Nutrition, University Hospitals Virgen del Rocío, 41013 Seville, Spain

3. Faculty of Medicine, University of Seville, 41009 Seville, Spain

4. Endocrinology and Nutrition Clinical Management Unit, University Hospital Valme, 41014 Seville, Spain

5. Biomedical Research Institute of Málaga (IBIMA), 29010 Málaga, Spain

6. Endocrinology and Nutrition Clinical Management Unit, Regional University Hospital of Málaga/University of Málaga, 29010 Málaga, Spain

7. Biomedical Network Research Centre for Diabetes and Associated Metabolic Diseases (CIBERDEM) (CB07/08/0019), Health institute Carlos III, 28029 Madrid, Spain

8. Medicine and Dermatology Department, Faculty of Medicine, University of Málaga, 29010 Málaga, Spain

9. University Hospital of Jaén, 23007 Jaén, Spain

10. Endocrinology and Nutrition Clinical Management Unit, University Hospital Reina Sofia, 14004 Córdoba, Spain

11. Endocrinology and Nutrition Clinical Management Unit, University Hospital Virgen Macarena, 41009 Seville, Spain

12. Endocrinology and Nutrition Clinical Management Unit, University Hospital San Cecilio, 18012 Granada, Spain

13. Biosanitary Institute of Granada, Medicine Department, Faculty of Medicine of Granada, University of Granada, 18010 Granada, Spain

14. Endocrinology and Nutrition Clinical Management Unit, University Hospital Virgen de la Victoria, 29010 Málaga, Spain

15. Endocrinology and Nutrition Clinical Management Unit, Internal Medicine Clinical Management Unit, Hospital Infanta Margarita, 14940 Cabra, Córdoba, Spain

16. University Hospital of Badajoz, 06080 Badajoz, Spain

17. Endocrinology and Nutrition Clinical Management Unit, University Hospital Torrecárdenas, 04009 Almeria, Spain

18. Endocrinology and Nutrition Clinical Management Unit, Biomedical Research and Innovation Institute of Cádiz, University Hospital Puerta del Mar, 11009 Cádiz, Spain

Abstract

(1) Background: Hyperglycaemia that occurs during enteral nutrition (EN) should be prevented and treated appropriately since it can have important consequences for morbidity and mortality. However, there are few quality studies in the literature regarding the management of EN in this situation. The objective of this project was to attempt to respond, through a panel of experts, to those clinical problems regarding EN in patients with diabetes or stress hyperglycaemia (hereinafter referred to only as hyperglycaemia) for which we do not have conclusive scientific evidence; (2) Methods: The RAND/UCLA Appropriateness Method, a modified Delphi panel method, was applied. A panel of experts made up of 10 clinical nutrition specialists was formed, and they scored on the appropriateness of EN in hyperglycaemia, doing so in two rounds. A total of 2992 clinical scenarios were examined, which were stratified into five chapters: type of formula used, method of administration, infusion site, treatment of diabetes, and gastrointestinal complications. (3) Results: consensus was detected in 36.4% of the clinical scenarios presented, of which 23.7% were deemed appropriate scenarios, while 12.7% were deemed inappropriate. The remaining 63.6% of the scenarios were classified as uncertain; (4) Conclusions: The recommendations extracted will be useful for improving the clinical management of these patients. However, there are still many uncertain scenarios reflecting that the criteria for the management of EN in hyperglycaemia are not completely standardised. More studies are required to provide quality recommendations in this area.

Funder

FRESENIUS KABI

Publisher

MDPI AG

Subject

Food Science,Nutrition and Dietetics

Reference27 articles.

1. Stress Hyperglycemia: An Essential Survival Response!;Marik;Crit. Care Med.,2013

2. Hyperglycemia: An Independent Marker of in-Hospital Mortality in Patients with Undiagnosed Diabetes;Cakir;J. Clin. Endocrinol. Metab.,2003

3. Recomendaciones Del Grupo GARIN Para El Manejo de Pacientes No Críticos Con Diabetes o Hiperglucemia de Estrés y Nutrición Artificial;Olveira;Nutr. Hosp.,2012

4. Evidence-Based Recommendations and Expert Consensus on Enteral Nutrition in the Adult Patient with Diabetes Mellitus or Hyperglycemia;Olveira;Nutrition,2017

5. Prevalence of Diabetes Mellitus in Patients with Home Enteral Nutrition;Olveira;Endocrinol. Diabetes Nutr.,2020

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