CochleRob: Parallel-Serial Robot to Position a Magnetic Actuator around a Patient’s Head for Intracochlear Microrobot Navigation

Author:

Nadour Housseyne1ORCID,Bozorg Grayeli Alexis23ORCID,Poisson Gérard4ORCID,Belharet Karim5

Affiliation:

1. Centre National de la Recherche Scientifique (CNRS), GIPSA-Lab, École Doctorale Électronique, Électrotechnique, Automatique, Traitement du Signal (ED EEATS), 38100 Grenoble, France

2. Department of Otolaryngology-Head and Neck Surgery, Dijon University Hospital, 21000 Dijon, France

3. CNRS UMR 6306 Le2i Research Laboratory, 21078 Dijon, France

4. PRISME EA 4229, Université d’Orléans, 45100 Orléans, France

5. PRISME EA 4229, JUNIA-HEI, 2 Allée Jean Vaillé, 36000 Châteauroux, France

Abstract

Our work introduces a new robotic solution named CochleRob, which is used for the administration of super-paramagnetic antiparticles as drug carriers into the human cochlea for the treatment of hearing loss caused by damaged cochlea. This novel robot architecture presents two key contributions. First, CochleRob has been designed to meet specifications pertaining to ear anatomy, including workspace, degrees of freedom, compactness, rigidity, and accuracy. The first objective was to develop a safer mathod to administer drugs to the cochlea without the need for catheter or CI insertion. Secondly, we aimed at developing and validating the mathemathical models, including forward, inverse, and dynamic models, to support the robot function. Our work provides a promising solution for drug administration into the inner ear.

Funder

the CochleRob project, founded by JUNIA-HEI Châteauroux, Châteauroux Métropole and Région Centre-Val de Loire, in France

Publisher

MDPI AG

Subject

Electrical and Electronic Engineering,Biochemistry,Instrumentation,Atomic and Molecular Physics, and Optics,Analytical Chemistry

Reference44 articles.

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2. Modeling, design, and evaluation of a parallel robot for cochlear implant surgery;Pile;IEEE/ASME Trans. Mechatron.,2014

3. Validation of cochlear implant electrode localization techniques;Zhao;Medical Imaging 2018: Image-Guided Procedures, Robotic Interventions, and Modeling,2018

4. Initial results with image-guided cochlear implant programming in children;Noble;Otol. Neurotol. Off. Publ. Am. Otol. Soc. Am. Neurotol. Soc. Eur. Acad. Otol. Neurotol.,2016

5. Caversaccio, M., Wimmer, W., Anso, J., Mantokoudis, G., Gerber, N., Rathgeb, C., Schneider, D., Hermann, J., Wagner, F., and Scheidegger, O. (2019). Robotic middle ear access for cochlear implantation: First in man. PLoS ONE, 14.

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