Dietary Supplementation of Lactobacillus johnsonii RS-7 Improved Antioxidant and Immune Function of Weaned Piglets

Author:

Zhao Kai12,Yin Heng1,Yan Honglin1ORCID,Tang Wenjie3,Diao Hui3,Wang Qi4,Qi Renli4ORCID,Liu Jingbo1

Affiliation:

1. School of Life Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, China

2. Yibin Municipal Bureau of Agriculture and Rural Affairs, Yibin 644000, China

3. Livestock and Poultry Biological Products Key Laboratory of Sichuan Province, Sichuan Animtech Feed Co., Ltd., Chengdu 610066, China

4. Chongqing Academy of Animal Science, Chongqing 402460, China

Abstract

We investigated the effects of dietary supplementation of lactic acid bacteria on the immune and antioxidant performance of weaned pigs. A total of 128 Duroc × Landrace × Yorkshire piglets weaned on day 28 with an average body weight of 8.95 ± 1.15 kg were selected and randomly divided into four treatment groups according to body weight and sex for a 28-day study. The four dietary treatments were basal diet (CON), and CON with 0.05% (LJ0.05), 0.1% (LJ0.1), and 0.2% (LJ0.2) Lactobacillus johnsonii RS-7, respectively. The lowest feed-to-gain ratio (F:G) was found when LJ0.1 was added to the diet. The addition of compound lactic acid bacteria to the diet increased the concentrations of TP, ALB, IgA, and IgM on day 14 and IgG, IgA, and IgM on day 28 (p < 0.05) in the blood, with trait values greater for pigs fed LJ0.1 than CON pigs (p < 0.05). Concentrations of antioxidants (CAT, T-AOC, MDA, T-SOD, and GSH) in serum, intestinal mucosa, spleen, liver, and pancreas improved. In summary, dietary supplementation of Lactobacillus johnsonii RS-7 improved the antioxidant and immune function of weaned piglets.

Funder

Strategic Priority Research Program of the National Center of Technology Innovation for Pigs

Publisher

MDPI AG

Subject

General Veterinary,Animal Science and Zoology

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