Molecular Dynamics Simulation Reveals Specific Interaction Sites between Scorpion Toxins and Kv1.2 Channel: Implications for Design of Highly Selective Drugs-Reference-Cited by-同舟云学术

Molecular Dynamics Simulation Reveals Specific Interaction Sites between Scorpion Toxins and Kv1.2 Channel: Implications for Design of Highly Selective Drugs

Published:2017-11-01 Issue:11 Volume:9 Page:354
ISSN:2072-6651
Container-title:Toxins
language:en
Short-container-title:Toxins

Author:

Yuan Shouli,Gao Bin,Zhu Shunyi^ORCID

Publisher

MDPI AG

Subject

Health, Toxicology and Mutagenesis,Toxicology

Link

http://www.mdpi.com/2072-6651/9/11/354/pdf

Reference61 articles.

1. Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement

2. Voltage-gated potassium channels as therapeutic targets

3. Structural and Functional Elucidation of Peptide Ts11 Shows Evidence of a Novel Subfamily of Scorpion Venom Toxins

4. A New Kv1.2 Channelopathy Underlying Cerebellar Ataxia

5. Seizures and Reduced Life Span in Mice Lacking the Potassium Channel Subunit Kv1.2, but Hypoexcitability and Enlarged Kv1 Currents in Auditory Neurons

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