Transcatheter Aortic Valve Therapy for Bicuspid Aortic Valve Stenosis

Author:

Dayawansa Nalin H.123,Noaman Samer14,Teng Lung En1,Htun Nay Min15

Affiliation:

1. Alfred Health, Melbourne, VIC 3004, Australia

2. Department of Medicine, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia

3. Baker Heart & Diabetes Institute, Melbourne, VIC 3004, Australia

4. Western Health, St Albans, VIC 3021, Australia

5. Peninsula Health, Frankston, VIC 3199, Australia

Abstract

Transcatheter aortic valve implantation (TAVI) has become first-line treatment for older adults with severe aortic stenosis (AS), however, patients with bicuspid aortic valve (BAV) have been traditionally excluded from randomised trials and guidelines. As familiarity and proficiency of TAVI operators have improved, case-series and observational data have demonstrated the feasibility of successful TAVI in bicuspid aortic valve aortic stenosis (BAV-AS), however, patients with BAV-AS have several distinct characteristics that influence the likelihood of TAVI success. This review aims to summarise the pathophysiology and classification of BAV, published safety data, anatomical challenges and procedural considerations essential for pre-procedural planning, patient selection and procedural success of TAVI in BAV.

Funder

Australian Government Research Training Program (RTP) Scholarship

Baker Heart & Diabetes Bright Sparks Scholarship

Publisher

MDPI AG

Subject

Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics

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