Abstract
During the last few decades, the effective population size of indigenous zebu cattle breeds has declined drastically, resulting in the classification of some of them into the vulnerable, endangered, or critically endangered category. Drastic reductions in the effective size of a population may result in genetic bottlenecks and can affect within-breed genetic variability and its viability. The present study was undertaken with the objective of evaluating South Indian zebu cattle populations for mutation drift equilibrium and to detect the occurrence of recent genetic bottleneck events. A total of 293 cattle from eight indigenous breeds were genotyped at 27 FAO/ISAG-recommended microsatellite marker loci. Three different statistical tests, viz., the sign test, standardized differences test, and Wilcoxon sign rank test were performed using allele frequency data to detect loci with heterozygosity excess under the infinite alleles, stepwise, and two-phase mutation models. Under the infinite alleles model, the observed number of loci with heterozygosity excess (He > Heq) ranged between 10 and 19 among the investigated cattle breeds. However, the observed heterozygosity excess was not statistically significant (p > 0.05) in any of the studied breeds. Similarly, the standardized differences test and Wilcoxon sign rank test revealed no concrete evidence for the occurrence of a recent genetic bottleneck in South Indian zebu cattle breeds. The qualitative test for mode-shift distortion revealed a normal L-shaped distribution of allele frequencies, suggesting a lack of evidence for the loss of low-frequency alleles in all the investigated South Indian zebu cattle breeds.
Funder
Coordinated Research Project by Joint FAO/IAEA Division, International Atomic Energy Agency, Vienna
Subject
General Veterinary,Animal Science and Zoology
Reference30 articles.
1. Cattle demographic history modelled from autosomal sequence variation
2. Mitochondrial genomes of extinct aurochs survive in domestic cattle
3. Evidence for two independent domestications of cattle.
4. The Second Report on the State of the World’s Animal Genetic Resources for Food and Agriculture,2015
5. Livestock Census: 20th Livestock Census of India-Key Results; Ministry of Fisheries, Animal Husbandry and Dairying, Department of Animal Husbandry and Dairying: Krishi Bhavan, India, 2019