Treatment of Patients with Mild to Moderate Ulcerative Colitis: A Middle East Expert Consensus

Author:

Awadhi Sameer Al1ORCID,Alboraie Mohamed2ORCID,Albaba Emad Aldin3,Almutairdi Abdulelah4,Alsaad Monther5,Azzam Nahla6,Barakat Husam7,D’Amico Ferdinando89,Danese Silvio8,El Kady Mohamed10,Ghoneim Hossam11,Hamoudi Waseem12ORCID,Jazzar Ahmad13,Mosli Mahmoud14ORCID,Shehab Hany15,Sneineh Awni Abu16

Affiliation:

1. Digestive Diseases Unit, Rashid Hospital, Dubai 003206, United Arab Emirates

2. Department of Internal Medicine, Al-Azhar University, Cairo 11884, Egypt

3. Department of Medicine, Almana General Hospital, Alkhobar 31952, Saudi Arabia

4. Department of Medicine, King Faisal Specialist Hospital and Research Center, Riyadh 11564, Saudi Arabia

5. Al Madar Medical Centre, Sharjah P.O. Box 80789, United Arab Emirates

6. Division of Gastroenterology, Department of Medicine, College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia

7. Department of Gastroenterology, Yarmouk University, Irbid 21163, Jordan

8. Gastroenterology and Endoscopy, IRCCS Ospedale San Raffaele and Vita-Salute San Raffaele University, 20132 Milan, Italy

9. Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, 20132 Milan, Italy

10. Department of Medical Pharmacology, Faculty of Medicine, Cairo University, Cairo 11559, Egypt

11. Immunology and Allergy Department, Medical Research Institute, Alexandria University, Alexandria 5424041, Egypt

12. Internal Medicine Department, Al-Bashir Hospital, Amman 11151, Jordan

13. Gastroenterology Division, Sheikh Khalifa Medical City, Abu Dhabi 51900, United Arab Emirates

14. Department of Medicine, King Abdulaziz University Hospital, Jeddah 21589, Saudi Arabia

15. Integrated Clinical and Research Center for Intestinal Disorders (ICRID), Gastroenterology Division, Endemic Medicine Department, Cairo University, Cairo 3725121, Egypt

16. Gastroenterology and Hepatology, University of Jordan, Amman 11942, Jordan

Abstract

The prevalence of ulcerative colitis (UC) in the Middle East is increasing, impacting the economic and healthcare burden. The management of patients with mild to moderate UC is still a challenge as several factors can affect optimal care, including drug choice, induction and maintenance dose, treatment optimization and de-escalation, therapy duration, monitoring, and safety profile. We conducted an expert consensus to standardize the management of patients with mild to moderate UC. Sixteen experts in inflammatory bowel diseases, through a well-established and accepted Delphi methodology, voted and approved eight statements in order to provide practical guidance to clinicians in the Middle East.

Funder

Ferring

Publisher

MDPI AG

Subject

General Medicine

Reference65 articles.

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