Microwave-Based Dielectric Properties as an Electrophysiological Biomarker: Future Perspectives

Author:

Cherukuri Akhila Sai Sree1,Modi Vaishnavi Kalpesh1,Baraskar Bhavana2,Sood Shubham3ORCID,Reguram Reshma1,Palvia Divyanshi1,Gopalakrishnan Keerthy14,Damani Devanshi N.56ORCID,Gaddam Sunil1,Samaddar Poulami1ORCID,Katukuri Nishanth1ORCID,Shivaram Suganti7,Dey Shuvashis18ORCID,Mitra Dipankar19,Roy Sayan110ORCID,Linden David R.11,Beyder Arthur311,Kulkarni Kanchan1213ORCID,Arunachalam Shivaram P.123414ORCID

Affiliation:

1. Microwave Engineering and Imaging Laboratory (MEIL), Division of Gastroenterology & Hepatology, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA

2. Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA

3. Division of Gastroenterology & Hepatology, Mayo Clinic, Rochester, MN 55905, USA

4. GIH Artificial Intelligence Laboratory (GAIL), Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA

5. Department of Internal Medicine, Texas Tech University Health Science Center, El Paso, TX 79995, USA

6. Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USA

7. Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA

8. Department of Electrical and Computer Engineering, North Dakota State University, Fargo, ND 58105, USA

9. Department of Computer Science and computer Engineering, University of Wisconsin-La Crosse, La Crosse, WI 54601, USA

10. Department of Electrical Engineering and Computer Science, South Dakota Mines, Rapid City, SD 57701, USA

11. Department of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA

12. IHU-LIRYC, Electrophysiology and Heart Modeling Institute, Fondation Bordeaux Université, Pessac, 33600 Bordeaux, France

13. INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, University of Bordeaux, U1045, 33000 Bordeaux, France

14. Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA

Abstract

Electrophysiology is the study of the electrical properties of biological tissues, which involves the movement of ions across cell membranes. The analysis of the movement of electrical charges through the body has a wide range of biomedical applications, such as diagnosing and planning treatment in cardiovascular, nervous systems, muscular, and gastrointestinal disorders. The dielectric properties of biological tissues change according to the water content in the tissue and are measured as permittivity and conductivity relative to the frequency of the electrical field. This principle has been applied in diagnostics and therapeutics using microwave energysuch as imaging and ablation, etc. This review article summarizes the potential use of measuring dielectric properties using microwave imaging and how it can augment electrophysiological studies in medicine.

Funder

2021 Gastroenterology and Hepatology (GIH) innovation

GIH Division

Mayo Clinic

Publisher

MDPI AG

Subject

Electrical and Electronic Engineering,Computer Networks and Communications,Hardware and Architecture,Signal Processing,Control and Systems Engineering

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