A Review of Dendrophthoe pentandra (Mistletoe): Phytomorphology, Extraction Techniques, Phytochemicals, and Biological Activities

Author:

Awang Mohd Azrie12ORCID,Nik Mat Daud Nik Nurul Najihah3,Mohd Ismail Nurul Izzati4,Abdullah Farah Izana5ORCID,Benjamin Mohammad Amil Zulhilmi6ORCID

Affiliation:

1. Faculty of Food Science and Nutrition, Universiti Malaysia Sabah, Jalan UMS, Kota Kinabalu 88400, Sabah, Malaysia

2. Innovative Food Processing and Ingredient Research Group, Faculty of Food Science and Nutrition, Universiti Malaysia Sabah, Jalan UMS, Kota Kinabalu 88400, Sabah, Malaysia

3. Faculty of Medicine, Universiti Sultan Zainal Abidin Kampus Perubatan, Kuala Terengganu 20400, Terengganu Darul Iman, Malaysia

4. Department of Science and Mathematics, Centre for Diploma Studies, Universiti Tun Hussein Onn Malaysia, Hab Pendidikan Tinggi Pagoh, KM 1, Jalan Panchor, Panchor 84600, Johor, Malaysia

5. International Institute of Aquaculture and Aquatic Sciences (I-AQUAS), Universiti Putra Malaysia, Lot 960 Jln Kemang 6, Port Dickson 71050, Negeri Sembilan, Malaysia

6. Borneo Research on Algesia, Inflammation and Neurodegeneration (BRAIN) Group, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Jalan UMS, Kota Kinabalu 88400, Sabah, Malaysia

Abstract

Dendrophtoe pentandra, popularly known as mistletoe, is a semi-parasitic plant that can grow on many host plants and is native to Southeast Asia, especially Malaysia. D. pentandra is regarded as an unfavourable plant for an economically significant horticultural plant; however, D. pentandra is also regarded as a medicinal plant and is used in traditional and alternative medicine to treat coughs, diabetes, hypertension, and cancer. Scientific research has also found that this plant has significant potential for medical properties such as antioxidant, antibacterial, anticancer, antiproliferative, antidiabetic and antihyperglycaemic, anti-inflammatory, cytotoxicity, hepatoprotective, immunomodulatory, and anti-aging properties. Numerous phytochemical compounds from D. pentandra extracts have been identified using extraction techniques such as maceration and reflux. Thus, this review aims to provide thorough information on phytomorphology, extraction techniques, phytochemicals, biological activities, and the future prospects of D. pentandra.

Publisher

MDPI AG

Subject

Process Chemistry and Technology,Chemical Engineering (miscellaneous),Bioengineering

Reference81 articles.

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2. Jayanti, E.D. (2018). Uji Aktivitas Antibakteri Ekstrak Etanol dan Fraksi Daun Benalu Mangga Gadung (Dendrophthoe pentandra (L.) Miq.) terhadap Staphylococcus aureus ATCC 6538 Dan Escherichia coli ATCC 25922. [Undergraduate’s Thesis, Universitas Jember, Kabupaten Jember].

3. The bright side of parasitic plants: What are they good for?;Li;Plant Physiol.,2021

4. Isolation and identification of active antioxidant compound from star fruit (Averrhoa carambola) mistletoe (Dendrophthoe pentandra (L.) Miq.) ethanol extract;Artanti;J. Appl. Sci.,2006

5. Phytochemical analysis and antioxidant activity of leaves and flowers extracts of mistletoe (Dendrophthoe pentandra (L.) Miq.), collected from UI Campus, Depok;Alharits;AIP Conf. Proc.,2019

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