Novel Key Ingredients in Urinary Tract Health—The Role of D-mannose, Chondroitin Sulphate, Hyaluronic Acid, and N-acetylcysteine in Urinary Tract Infections (Uroial PLUS®)-Reference-Cited by-同舟云学术

Novel Key Ingredients in Urinary Tract Health—The Role of D-mannose, Chondroitin Sulphate, Hyaluronic Acid, and N-acetylcysteine in Urinary Tract Infections (Uroial PLUS®)

Published:2023-08-14 Issue:16 Volume:15 Page:3573
ISSN:2072-6643
Container-title:Nutrients
language:en
Short-container-title:Nutrients

Author:

Crocetto Felice¹^ORCID,Balsamo Raffaele²,Amicuzi Ugo³,De Luca Luigi⁴,Falcone Alfonso¹,Mirto Benito Fabio¹,Giampaglia Gaetano¹,Ferretti Gianpiero¹,Capone Federico¹,Machiella Fabio¹,Varriale Domenico¹,Sicignano Enrico¹^ORCID,Pagano Giovanni¹,Lombardi Alessandro¹,Lucarelli Giuseppe⁵^ORCID,Lasorsa Francesco⁵^ORCID,Busetto Gian Maria⁶^ORCID,Del Giudice Francesco⁷^ORCID,Ferro Matteo⁸^ORCID,Imbimbo Ciro¹,Barone Biagio³^ORCID

Affiliation:

1. Department of Neurosciences and Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80131 Naples, Italy

2. Urology Unit, AORN Ospedali dei Colli, Monaldi Hospital, 80131 Naples, Italy

3. Division of Urology, Department of Surgical Sciences, AORN Sant’Anna e San Sebastiano, 81100 Caserta, Italy

4. Division of Urology, Department of Surgical Multispecialty, AORN Antonio Cardarelli, 80131 Naples, Italy

5. Urology, Andrology and Kidney Transplantation Unit, Department of Emergency and Organ Transplantation, University of Bari, 70124 Bari, Italy

6. Department of Urology and Organ Transplantation, University of Foggia, 71121 Foggia, Italy

7. Department of Maternal Infant and Urologic Sciences, Policlinico Umberto I Hospital, Sapienza University of Rome, 00161 Rome, Italy

8. Department of Urology, IEO—European Institute of Oncology, IRCCS—Istituto di Ricovero e Cura a Carattere Scientifico, 20141 Milan, Italy

Abstract

Urinary tract infections represent a common and significant health concern worldwide. The high rate of recurrence and the increasing antibiotic resistance of uropathogens are further worsening the current scenario. Nevertheless, novel key ingredients such as D-mannose, chondroitin sulphate, hyaluronic acid, and N-acetylcysteine could represent an important alternative or adjuvant to the prevention and treatment strategies of urinary tract infections. Several studies have indeed evaluated the efficacy and the potential use of these compounds in urinary tract health. In this review, we aimed to summarize the characteristics, the role, and the application of the previously reported compounds, alone and in combination, in urinary tract health, focusing on their potential role in urinary tract infections.

Publisher

MDPI AG

Subject

Food Science,Nutrition and Dietetics

Link

https://www.mdpi.com/2072-6643/15/16/3573/pdf

Reference94 articles.

1. Urinary Tract Infections: Epidemiology, Mechanisms of Infection and Treatment Options;Walker;Nat. Rev. Microbiol.,2015

2. An Introduction to the Epidemiology and Burden of Urinary Tract Infections;Medina;Ther. Adv. Urol.,2019

3. Urinary Tract Infection in Women;Czajkowski;Prz. Menopauzalny,2021

4. Sexual Intercourse and Risk of Symptomatic Urinary Tract Infection in Post-Menopausal Women;Moore;J. Gen. Intern. Med.,2008

5. Urinary Tract Infection in Postmenopausal Women;Raz;Korean J. Urol.,2011