1. Moscow Institute of Physics and Technology, 9 Institutsky Lane, Dolgoprudny, Moscow 141701, Russia
2. Department of Biological Sciences, University of Lethbridge, Lethbridge, AB T1K 3M4, Canada
3. Pathway Rx., 2 Fortress Rise SW, Calgary, AB T3H 4Z2, Canada
4. Biomedical and Health Informatics, Computer Science Department, State University of New York, 2 S Clinton St, Syracuse, NY 13202, USA