Personalized Interventional Surgery of the Lumbar Spine: A Perspective on Minimally Invasive and Neuroendoscopic Decompression for Spinal Stenosis

Author:

Lewandrowski Kai-Uwe1234ORCID,Yeung Anthony56,Lorio Morgan P.7,Yang Huilin8,Ramírez León Jorge Felipe29,Sánchez José Antonio Soriano10,Fiorelli Rossano Kepler Alvim11,Lim Kang Taek12,Moyano Jaime13,Dowling Álvaro1415,Sea Aramayo Juan Marcelo16,Park Jeong-Yoon17,Kim Hyeun-Sung18ORCID,Zeng Jiancheng19,Meng Bin20,Gómez Fernando Alvarado21,Ramirez Carolina22,De Carvalho Paulo Sérgio Teixeira23,Rodriguez Garcia Manuel10,Garcia Alfonso24ORCID,Martínez Eulalio Elizalde25,Gómez Silva Iliana Margarita26,Valerio Pascua José Edgardo27,Duchén Rodríguez Luis Miguel28ORCID,Meves Robert29,Menezes Cristiano M.30,Carelli Luis Eduardo31,Cristante Alexandre Fogaça32ORCID,Amaral Rodrigo33,de Sa Carneiro Geraldo34,Defino Helton35,Yamamoto Vicky4363738,Kateb Babak4383940,

Affiliation:

1. Center for Advanced Spine Care of Southern Arizona, Tucson, AZ 85712, USA

2. Department of Orthopaedics, Fundación Universitaria Sanitas, Bogotá 111321, Colombia

3. Department of Orthopedics at Hospital Universitário Gaffree Guinle Universidade Federal do Estado do Rio de Janeiro, R. Mariz e Barros, 775-Maracanã, Rio de Janeiro 20270-004, Brazil

4. Brain Technology and Innovation Park, Pacific Palisades, CA 90272, USA

5. Desert Institute for Spine Care, 1635 E Myrtle Ave Suite 400, Phoenix, AZ 85020, USA

6. Department of Neurosurgery, University of New Mexico School of Medicine, 915 Camino de Salud NE Albuquerque, Albuquerque, NM 87106, USA

7. Advanced Orthopedics, 499 East Central Parkway, Altamonte Springs, FL 32701, USA

8. Department of Orthopedic Surgery, The First Affiliated Hospital of Soochow University, No. 899 Pinghai Road, Suzhou 215031, China

9. Minimally Invasive Spine Center Bogotá D.C. Colombia, Reina Sofía Clinic Bogotá D.C. Colombia, Bogotá 110141, Colombia

10. Spine Clinic, The American-Bitish Cowdray Medical Center I.A.P, Campus Santa Fe, Mexico City 05370, Mexico

11. Department of General and Specialized Surgery, Gaffrée e Guinle University Hospital, Federal University of the State of Rio de Janeiro (UNIRIO), Rio de Janeiro 20000-000, Brazil

12. Good Doctor Teun Teun Spine Hospital, Seoul 775 , Republic of Korea

13. Torres Médicas Hospital Metropolitano, San Gabriel y Nicolás Arteta Torre Médica 3, Piso 5, Quito 170521, Ecuador

14. DWS Spine Clinic Center, CENTRO EL ALBA-Cam. El Alba 9500, Of. A402, Región Metropolitana, Las Condes 9550000, Chile

15. Department of Orthopaedic Surgery, Faculdade de Medicina de Ribeirão Preto (FMRP) da Universidade de São Paulo (USP), Ribeirão Preto 14040-900, Brazil

16. Hospital Obrero N°1, C. Lucas Jaimes 76, La Paz 0201-0220, Bolivia

17. Department of Neurosurgery, Spine and Spinal Cord Institute, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 731, Republic of Korea

18. Department of Neurosurgery, Nanoori Hospital Gangnam Hospital, Seoul 731, Republic of Korea

19. Department of Orthopaedic Surgery, West China Hospital Sichuan University, Chengdu 610041, China

20. Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou 215005, China

21. Santa Fe Foundation and Instituto Roosevelt, Bogotá 110311, Colombia

22. Centro de Cirugía Mínima Invasiva—CECIMIN, Avenida Carrera 45 # 104–76, Bogotá 0819, Colombia

23. Department of Neurosurgery, Pain and Spine Minimally Invasive Surgery Service at Gaffree Guinle University Hospital, Rio de Janeiro 20270-004, Brazil

24. Department of Orthopaedic Surgery, Espalda Saludable, Hospital Angeles Tijuana, Tijuana 22010, Mexico

25. Department of Spine Surgery, Hospital de Ortopedia, UMAE “Dr. Victorio de la Fuente Narvaez”, Ciudad de México 07760, Mexico

26. Department of Spine Surgery, Hospital Ángeles Universidad, Av Universidad 1080, Col Xoco, Del Benito Juárez, Ciudad de México 03339, Mexico

27. Department of Neurosurgery, Palmetto Steward General Hospital, South Miami, FL 33143, USA

28. Center for Neurological Diseases, Bolivian Spine Association, Spine Chapter of Latin American Federation of Neurosurgery Societies, Public University of El Alto, La Paz 0201-0220, Bolivia

29. Santa Casa Spine Center, São Paulo 09015-000, Brazil

30. Universidade Federal de Minas Gerais (UFMG), Belo Horizonte 31270-901, Brazil

31. Instituto Nacional Traumato-Ortopedia-INTO, Rio de Janeiro 20940-070, Brazil

32. Department of Orthopaedic Surgery, University of São Paulo (USP), São Paulo 05508-060, Brazil

33. Instituto de Patologia da Coluna (IPC), Faculdade de Medicina de Ribeirão Preto (FMRP) da Universidade de São Paulo (USP), São Paulo 14040-900, Brazil

34. Department of Orthopaedic Surgery, Hospital da Restauração, Recife 52171-011, Brazil

35. Hospital das Clínicas of Ribeirao Preto Medical School, Sao Paulo University, Ribeirão Preto 14040-900, Brazil

36. The USC Caruso Department of Otolaryngology-Head and Neck Surgery, USC Keck School of Medicine, Los Angeles, CA 90033, USA

37. USC-Norris Comprehensive Cancer Center, Los Angeles, CA 90033, USA

38. World Brain Mapping Foundation (WBMF), Pacific Palisades, CA 90272, USA

39. Society for Brain Mapping and Therapeutics (SBMT), Pacific Palisades, CA 90272, USA

40. National Center for Nano Bio Electronic (NCNBE), Los Angeles, CA 90272, USA

Abstract

Pain generator-based lumbar spinal decompression surgery is the backbone of modern spine care. In contrast to traditional image-based medical necessity criteria for spinal surgery, assessing the severity of neural element encroachment, instability, and deformity, staged management of common painful degenerative lumbar spine conditions is likely to be more durable and cost-effective. Targeting validated pain generators can be accomplished with simplified decompression procedures associated with lower perioperative complications and long-term revision rates. In this perspective article, the authors summarize the current concepts of successful management of spinal stenosis patients with modern transforaminal endoscopic and translaminar minimally invasive spinal surgery techniques. They represent the consensus statements of 14 international surgeon societies, who have worked in collaborative teams in an open peer-review model based on a systematic review of the existing literature and grading the strength of its clinical evidence. The authors found that personalized clinical care protocols for lumbar spinal stenosis rooted in validated pain generators can successfully treat most patients with sciatica-type back and leg pain including those who fail to meet traditional image-based medical necessity criteria for surgery since nearly half of the surgically treated pain generators are not shown on the preoperative MRI scan. Common pain generators in the lumbar spine include (a) an inflamed disc, (b) an inflamed nerve, (c) a hypervascular scar, (d) a hypertrophied superior articular process (SAP) and ligamentum flavum, (e) a tender capsule, (f) an impacting facet margin, (g) a superior foraminal facet osteophyte and cyst, (h) a superior foraminal ligament impingement, (i) a hidden shoulder osteophyte. The position of the key opinion authors of the perspective article is that further clinical research will continue to validate pain generator-based treatment protocols for lumbar spinal stenosis. The endoscopic technology platform enables spine surgeons to directly visualize pain generators, forming the basis for more simplified targeted surgical pain management therapies. Limitations of this care model are dictated by appropriate patient selection and mastering the learning curve of modern MIS procedures. Decompensated deformity and instability will likely continue to be treated with open corrective surgery. Vertically integrated outpatient spine care programs are the most suitable setting for executing such pain generator-focused programs.

Publisher

MDPI AG

Subject

Medicine (miscellaneous)

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