Functionally Significant Variants in Genes Associated with Abdominal Obesity: A Review-Reference-Cited by-同舟云学术

Functionally Significant Variants in Genes Associated with Abdominal Obesity: A Review

Published:2023-03-01 Issue:3 Volume:13 Page:460
ISSN:2075-4426
Container-title:Journal of Personalized Medicine
language:en
Short-container-title:JPM

Author:

Bairqdar Ahmad¹^ORCID,Ivanoshchuk Dinara¹²^ORCID,Shakhtshneider Elena¹²

Affiliation:

1. Federal Research Center Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Prospekt Akad. Lavrentyeva 10, Novosibirsk 630090, Russia

2. Institute of Internal and Preventive Medicine—Branch of Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Bogatkova Str. 175/1, Novosibirsk 630004, Russia

Abstract

The high prevalence of obesity and of its associated diseases is a major problem worldwide. Genetic predisposition and the influence of environmental factors contribute to the development of obesity. Changes in the structure and functional activity of genes encoding adipocytokines are involved in the predisposition to weight gain and obesity. In this review, variants in genes associated with adipocyte function are examined, as are variants in genes associated with metabolic aberrations and the accompanying disorders in visceral obesity.

Funder

Russian Science Foundation

Publisher

MDPI AG

Subject

Medicine (miscellaneous)

Link

https://www.mdpi.com/2075-4426/13/3/460/pdf

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