Acquired and Transmitted Multidrug-Resistant Tuberculosis among the Incarcerated Population and Its Determinants in the State of Paraná—Brazil
-
Published:2022-11-12
Issue:22
Volume:19
Page:14895
-
ISSN:1660-4601
-
Container-title:International Journal of Environmental Research and Public Health
-
language:en
-
Short-container-title:IJERPH
Author:
Santos Márcio Souza dosORCID,
Pieri Flávia Meneguetti,
Berra Thaís ZamboniORCID,
Scholze Alessandro Rolim,
Ramos Antônio Carlos Vieira,
de Almeida Crispim Juliane,
Giacomet Clóvis Luciano,
Alves Yan Mathias,
da Costa Fernanda Bruzadelli Paulino,
Moura Heriederson Sávio Dias,
Teibo Titilade Kehinde Ayandeyi,
Alonso Jonas Bodini,
Freitas Giselle Lima de,
Arcêncio Ricardo Alexandre
Abstract
(1) Background: Tuberculosis remains a public health problem in the world. The study analyzed the factors associated with drug-resistant tuberculosis in the prison population of the state of Paraná. (2) Methods: Ecological study of drug-resistant tuberculosis cases registered in the Paraná Information System, Brazil (2008 to 2018). We performed descriptive statistics of quantitative parameters calculated with absolute frequencies. Additionally, we used binary regression logistics, where the odds ratio with its respective confidence interval was calculated. (3) Results: Of the 653 cases registered as cases of tuberculosis in the incarcerated population, 98 were drug-resistant tuberculosis. We observed that educational level of up to 8 to 11 years of schooling, negative bacterial culture (test outcome) and no tobacco use were factors associated with the non-development of drug-resistant tuberculosis, while clinically confirmed pulmonary TB and positive sputum smear microscopy in the fourth month of follow-up showed an association for the development of drug resistance. (4) Conclusions: The study showed that clinically confirmed pulmonary TB and a positive sputum smear microscopy in the fourth month of follow-up were associated with drug-resistant tuberculosis.
Funder
National Council for Scientific and Technological Development—CNPq
Research Support Foundation of the State of São Paulo—FAPESP
Subject
Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health
Reference30 articles.
1. Available online: https://www.who.int/teams/global-tuberculosis-programme/tb-reports/global-tuberculosis-report-2021. Global Tuberculosis Report 2021, 2022.
2. Health Surveillance Secretariat. Epidemiological Bulletin 2021, 22v, 52, Jun. 2022.
3. Recommendations Manual for Tuberculosis Control in Brazil. 2022.
4. Droznin, M., Johnson, A., and Johnson, A.M. Multidrug resistant tuberculosis in prisons located in former Soviet countries: A systematic review. PLoS ONE, 2017. 12.
5. Special Epidemiological Bulletin. v. 1, March 2020. 2022.