Evaluating the Oral-Health-Related Quality of Life of Oral Submucous Fibrosis Patients before and after Treatment Using the OHIP-14 Tool

Author:

Memon Abdul Bari,Rahman Aneela Atta Ur,Channar Kashif Ali,Zafar Muhammad SohailORCID,Kumar NareshORCID

Abstract

The objective of the present study was to assess the oral-health-related quality of life (OHRQoL) of oral submucous fibrosis (OSMF) patients before and after standard treatment. A convenient sampling technique was used to recruit the clinically diagnosed patients of OSMF (n = 130). Based on the medical treatment, the patients were randomly divided into two study groups (group A and B). The group A patients received submucosal intralesional injections of dexamethasone (2 mL; 4 gm/mL), while group B patients received hyaluronidase (1500 IU). Both the group A and B patients received respective medical therapy biweekly for a period of five weeks. At the follow up visit (6 months), the impact of treatment on OHRQoL was assessed using the Oral Health Impact Profile-14 (OHIP-14). Data were analyzed by a chi-square test for quantitative variables and an independent t-test for qualitative variables. The comparison of all clinical parameters before and after treatment was performed by a paired t-test. The results after treatment showed that there was a significant improvement in all domains of OHIP-14 (p = 0.001) except psychological disability (p = 0.243). In addition, the OHRQoL of patients was significantly improved following the treatment.

Funder

Liaquat University of Medical & Health Sciences

Publisher

MDPI AG

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference44 articles.

1. A randomized control trial measuring the effectiveness of a mouth-exercising device for mucosal burning in oral submucous fibrosis

2. Oral submucous fibrosis: A chronic deliberating disease of oral cavity;Tanwir;Iran. J. Pathol.,2011

3. Clinical Efficacy of a Mouth-Exercising Device Adjunct to Local Ointment, Intra-Lesional Injections and Surgical Treatment for Oral Submucous Fibrosis: a Randomized Controlled Trial

4. Oral Pathology: Clinical Pathologic Correlations;Regezi,2016

5. Red and white lesions of the oral mucosa;Jontell;Burket’s Oral Med.,2008

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