Development of Nonwoven Fibrous Materials Based on Poly-3-Hydroxybutyrate with a High Content of α-Tricalcium Phosphate-Reference-Cited by-同舟云学术

Development of Nonwoven Fibrous Materials Based on Poly-3-Hydroxybutyrate with a High Content of α-Tricalcium Phosphate

Published:2023-07-26 Issue:15 Volume:15 Page:3167
ISSN:2073-4360
Container-title:Polymers
language:en
Short-container-title:Polymers

Author:

Tyubaeva Polina M.¹²^ORCID,Gasparyan Kristina G.¹²,Fedotov Alexander Yu.³,Lobzhanidze Pavel V.³,Baranov Oleg V.³^ORCID,Egorov Alexey A.³,Sirotinkin Vladimir P.³,Komlev Vladimir S.³^ORCID,Olkhov Anatoly A.¹²^ORCID

Affiliation:

1. Department of Physical Chemistry of Synthetic and Natural Polymer Compositions, Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 Kosygina Street, 119334 Moscow, Russia

2. Academic Department of Innovational Materials and Technologies Chemistry, Plekhanov Russian University of Economics, 36 Stremyanny Per., 117997 Moscow, Russia

3. A.A. Baikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences, Leninsky Prospect 49, 119334 Moscow, Russia

Abstract

α-tricalcium (α-TCP) phosphate is widely used as an osteoinductive biocompatible material, serving as an alternative to synthetic porous bone materials. The objective of this study is to obtain a highly filled fibrous nonwoven material composed of poly-3-hydroxybutyrate (PHB) and α-TCP and to investigate the morphology, structure, and properties of the composite obtained by the electrospinning method (ES). The addition of α-TCP had a significant effect on the supramolecular structure of the material, allowing it to control the crystallinity of the material, which was accompanied by changes in mechanical properties, FTIR spectra, and XRD curves. The obtained results open the way to the creation of new osteoconductive materials with a controlled release of the source of calcium into the living organism.

Publisher

MDPI AG

Subject

Polymers and Plastics,General Chemistry

Link

https://www.mdpi.com/2073-4360/15/15/3167/pdf

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