Development of a Model for Quantitative Assessment of Newborn Screening in Japan Using the Analytic Hierarchy Process

Author:

Konomura Keiko1ORCID,Hoshino Eri2,Sakai Kotomi3ORCID,Fukuda Takashi1,Tajima Go4

Affiliation:

1. Center for Outcomes Research and Economic Evaluation for Health (C2H), National Institute of Public Health, Wako-shi 351-0197, Japan

2. Division of Policy Evaluation, Department of Health Policy, Research Institute, National Center for Child Health and Development, Tokyo 157-8535, Japan

3. Comprehensive Unit for Health Economic Evidence Review and Decision Support (CHEERS), Research Organization of Science and Technology, Ritsumeikan University, Kyoto 600-8815, Japan

4. Division of Neonatal Screening, Research Institute, National Center for Child Health and Development, Tokyo 157-8535, Japan

Abstract

Whether or not conditions should be included in publicly funded newborn screening (NBS) programs should be discussed according to objective and transparent criteria. Certain criteria have been developed for the introduction of NBS programs in the context of individual countries; however, there are no standard selection criteria for NBS programs in Japan. This study aimed to develop a quantitative scoring model to assess newborn screening that incorporates the views of a variety of stakeholders in Japan. The five recommended eligibility criteria for NBS were stratified based on previous studies and expert opinions, using the analytic hierarchy process. We conducted a cross-sectional, web-based questionnaire targeting a wide range of people involved in NBS to investigate pairwise comparisons of the evaluation items between February and April of 2022. There were 143 respondents. Most of our respondents (44.1%) were physicians. Fifty-eight respondents (40.6%) had been engaged in NBS-related research or work for more than 10 years. The distribution of allocation points was the highest for ‘intervention’, ‘screening test’, ‘follow-up setting’, ’economic evaluation’, and ’disease/condition’, in that order. The algorithm in this study will guide decision makers in collecting and evaluating objective data, thus enabling transparent discussions to occur.

Funder

Japan Agency for Medical Research and Development

Publisher

MDPI AG

Subject

Obstetrics and Gynecology,Immunology and Microbiology (miscellaneous),Pediatrics, Perinatology and Child Health

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