Analysis of VOCs in Liquids through Vaporization in a Tubular Oven Monitored by Chemical Ionization Mass Spectrometry

Abstract

The analysis of chemical compounds present at trace levels in liquids is important not only for environmental measurements but also, for example, in the health sector. The reference technique for the analysis of Volatile Organic Compounds (VOCs) in liquids is GC, which is difficult to use with an aqueous matrix. In this work, we present an alternative technique to GC to analyze VOCs in water. A tubular oven is used to completely vaporize the liquid sample deposited on a gauze. The oven is heated in the presence of a dinitrogen flow, and the gas is analyzed at the exit of the oven by a chemical ionization mass spectrometer developed in our laboratory. It is a low magnetic field Fourier Transform Ion Cyclotron Resonance (FT-ICR) optimized for real-time analysis. The Proton Transfer Reaction (PTR) used during the Chemical Ionization event results in the selective ionization of the VOCs present in the gas phase. The optimization of the desorption conditions is described for the main operating parameters: temperature ramp, liquid quantity, and nitrogen flow. Their influence is studied using a 100 ppmv aqueous toluene solution. The analytical method is then tested on a mixture of seven VOCs.