Advances in the Treatment of Yaws

Author:

Marks MichaelORCID

Abstract

Yaws is one of the three endemic treponematoses and is recognised by the World Health Organization as a neglected tropical disease. Yaws is currently reported in 15 countries in the Pacific, South-East Asia, West and Central Africa, predominantly affects children, and results in destructive lesions of the skin and soft tissues. For most of the twentieth century penicillin-based treatment was the standard of care and resistance to penicillin has still not been described. Recently, oral azithromycin has been shown to be an effective treatment for yaws, facilitating renewed yaws eradication efforts. Resistance to azithromycin is an emerging threat and close surveillance will be required as yaws eradication efforts are scaled up globally.

Publisher

MDPI AG

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Immunology and Microbiology

Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Tréponème tropical;Médecine et Maladies Infectieuses Formation;2023-03

2. Other Treponema Species;Principles and Practice of Pediatric Infectious Diseases;2023

3. Conformity of yaws clinical features to combined rapid diagnostic test in children aged 2-15 years in an endemic area;The Journal of Infection in Developing Countries;2022-12-31

4. Natural-Product-Based Solutions for Tropical Infectious Diseases;Clinical Microbiology Reviews;2021-12-15

5. Marine Natural Products with Bioactivity Against Neglected Tropical Diseases;Topics in Heterocyclic Chemistry;2021

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