Determinants of Patients’ Adherence to Malaria Treatment in the Democratic Republic of the Congo

Author:

Ntamabyaliro Nsengi Y.ORCID,Burri ChristianORCID,Lula Yves N.,Nzolo Didier B.ORCID,Engo Aline B.,Ngale Mireille A.,Situakibanza Hippolyte N.,Mukomena Eric S.,Mesia Gauthier K.ORCID,Mampunza Samuel M.,Tona Gaston L.

Abstract

(1) Background: Malaria heavily affects the Democratic Republic of the Congo (DRC) despite the use of effective drugs. Poor adherence to malaria treatment may contribute to this problem. (2) Methods: In one rural and one urban health area in each of the 11 former provinces of the DRC, all households with a case of malaria in the 15 days preceding the survey were selected and the patients or caregivers were interviewed. Adherence to malaria treatment was assessed by self-declaration about its completion. Logistic regression was used to assess predictors. (3) Results: 1732 households participated. Quinine was the most used drug; adherence to artesunate–amodiaquine was the lowest and the main reason for treatment discontinuation was adverse reactions. Predictors of adherence were residence in an urban area, university education, catholic religion, and adoption of recommended behaviour towards a malaria case. Adherence was significantly lower for responders who obtained information on antimalarials from Community Health Workers (CHW). (4) Conclusions: Usage of recommended drugs and adherence to malaria treatment need to be promoted, especially in rural areas, and CHW involvement needs to be improved. Awareness messages need to be made accessible and comprehensible to poorly educated populations and churches need to be involved.

Funder

Global Fund to Fight AIDS, Tuberculosis and Malaria

Publisher

MDPI AG

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Immunology and Microbiology

Reference47 articles.

1. WHO Guidelines for Malaria, 16 February 2021,2021

2. Directives Nationales de Prise en Charge du Paludisme,2017

3. Adherence to antimalarial treatments in the real world—Does it really matter ?;Aspinall;Med. Malar. Ventur.,2015

4. How Patients Take Malaria Treatment: A Systematic Review of the Literature on Adherence to Antimalarial Drugs

5. Facts about Malaria https://www.ecdc.europa.eu/en/malaria/facts

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