Under-Reporting of Tuberculosis Disease among Children and Adolescents in Low and Middle-Income Countries: A Systematic Review

Author:

Linn Alexandra R.12,Dubois Melanie M.3,Steenhoff Andrew P.12

Affiliation:

1. Global Health Center, Children’s Hospital of Philadelphia & Department of Pediatrics, University of Pennsylvania, Philadelphia, PA 19104, USA

2. Department of Internal Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA

3. Division of Pediatric Infectious Diseases, Weill Cornell Medicine, New York, NY 10065, USA

Abstract

Under-reporting of tuberculosis (TB) disease in children and adolescents is a significant global concern, as many children are missing from TB notification data. A systematic literature review was conducted to understand the global reporting gap of child and adolescent TB as well as current interventions to close this gap in Low- and Middle- Income Countries (LMIC). Our study found large and variable gaps in child and adolescent TB reporting, due to various factors. Interventions to close this gap exist but are limited. Future studies are necessary to improve global surveillance systems to improve TB care delivery for children and adolescents.

Funder

CHOP Global Health Center

Melissa Ketunuti Memorial Fund

Publisher

MDPI AG

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Immunology and Microbiology

Reference45 articles.

1. World Health Organization (2023, March 05). Global Tuberculosis Report. Available online: https://www.who.int/teams/global-tuberculosis-programme/tb-reports/global-tuberculosis-report-2022.

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3. Burden of childhood tuberculosis in 22 high-burden countries: A mathematical modelling study;Dodd;Lancet Glob. Health,2014

4. Global impact of COVID-19 on childhood tuberculosis: An analysis of notification data;Ranasinghe;Lancet Glob. Health,2022

5. World Health Organization (2023, February 22). Assessment of Surveillance Data Workbook. Available online: https://cdn.who.int/media/docs/default-source/hq-tuberculosis/global-task-force-on-tb-impact-measurement/meetings/2010-11/3_workbook_en.pdf?sfvrsn=79a1aa86_3.

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