High Diversity and Transmission Dynamics of HIV-1 Non-C Subtypes in Bangladesh-Reference-Cited by-同舟云学术

High Diversity and Transmission Dynamics of HIV-1 Non-C Subtypes in Bangladesh

Published:2023-09-17 Issue:9 Volume:8 Page:451
ISSN:2414-6366
Container-title:Tropical Medicine and Infectious Disease
language:en
Short-container-title:TropicalMed

Author:

Sarker Md. Safiullah¹^ORCID,Jahan Rubiyat²

Affiliation:

1. Virology Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, Bangladesh

2. School of Business and Economics, North South University, Dhaka 1229, Bangladesh

Abstract

Genetic diversity and molecular epidemiology of HIV are directly relevant to HIV transmission. We report here the genetic diversity and transmission dynamics of non-C subtypes of HIV-1 strains detected in Bangladeshi key populations. Sequence analysis of gag gene revealed four subtypes A1, B, D, G, and nine CRFs (01_AE, 02_AG, 09_cpx, 10_CD, 15_AE/B, 13_cpx, 14_BG, 22_01_A1, and 25_AGU). Most of these non-C strains were detected in returnee migrant workers from different parts of the world. Phylogenetic analysis showed that the Bangladeshi HIV-1 strains detected in migrant workers and their wives and local sex workers shared common ancestries. The identification of the multiple subtypes indicates high diversity of non-C HIV-1 variants circulating in Bangladesh which might have been imported by migrant workers from multiple geographical areas.

Funder

icddr,b’s core funders and the Government of Bangladesh

Government of Bangladesh/DfID/IDA

UNAIDS, Family Health International (FHI), and icddr,b

Publisher

MDPI AG

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Immunology and Microbiology

Link

https://www.mdpi.com/2414-6366/8/9/451/pdf

Reference18 articles.

1. WHO (2023, August 18). World AIDS Day: Equalize to End the AIDS Epidemic. Available online: https://www.who.int/southeastasia/news/detail/30-11-2022-world-aids-day-equalize-to-end-the-aids-epidemic.

2. Park, B., Choi, Y., Kim, J.H., Seong, H., Kim, Y.J., Lee, M., Seong, J., Kim, S.-W., Song, J.Y., and Choi, H.-J. (2022). Mortality and Causes of Death among Individuals Diagnosed with Human Immunodeficiency Virus in Korea, 2004–2018: An Analysis of a Nationwide Population-Based Claims Database. Int. J. Environ. Res. Public Health, 19.

3. HIV.gov (2023, August 18). HIV and AIDS Epidemic Global Statistics, Available online: https://www.hiv.gov/hiv-basics/overview/data-and-trends/global-statistics/.

4. Islam, H. (2023, August 18). Bangladesh at High Risk of HIV Infection. Available online: https://www.risingbd.com/english/risingbd-special/news/84716.

5. Pachuau, L.N., Tannous, C., Chawngthu, R.L., and Agho, K.E. (2023). HIV and its associated factors among people who inject drugs in Mizoram, Northeast India. PLoS ONE, 18.