Detection of a Multiple Circulation Event of Dengue Virus 2 Strains in the Northern Region of Brazil-Reference-Cited by-同舟云学术

Detection of a Multiple Circulation Event of Dengue Virus 2 Strains in the Northern Region of Brazil

Published:2024-01-09 Issue:1 Volume:9 Page:17
ISSN:2414-6366
Container-title:Tropical Medicine and Infectious Disease
language:en
Short-container-title:TropicalMed

Author:

Amorim Murilo Tavares¹²,Naveca Felipe Gomes³⁴^ORCID,Hernández Leonardo Henrique Almeida²^ORCID,da Paz Thito Yan Bezerra²,da Silva de Oliveira Cintia Cryslaine¹,da Conceição Miranda Santos Alessandra²,Queiroz Alice Louize Nunes²^ORCID,Wanzeller Ana Lucia Monteiro²^ORCID,da Silva Eliana Vieira Pinto²,da Silva Fábio Silva²^ORCID,da Silva Sandro Patroca²^ORCID,Nunes Bruno Tardelli Diniz²^ORCID,Cruz Ana Cecília Ribeiro¹²^ORCID

Affiliation:

1. Institute of Biological Sciences, Federal University of Pará, Belém 66075-110, Brazil

2. Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Health and Environment Surveillance Secretariat, Ministry of Health, Ananindeua 67030-000, Brazil

3. Laboratory of Infectious Diseases Ecology in Amazon, Leonidas and Maria Deane Institute, Fiocruz, Manaus 69057-070, Brazil

4. Arbovirus and Hemorrhagic Virus Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-900, Brazil

Abstract

Dengue virus serotype 2 (DENV-2) is responsible for dengue epidemics on a global scale and is associated with severe cases of the disease. This study conducted a phylogenetic investigation of DENV-2 isolates from 2017 to 2021 originating from the northern states of Brazil. A total of 32 samples from DENV-2 isolates were analyzed, including 12 from Acre, 19 from Roraima, and one from Tocantins. Only one lineage of the Asian-American genotype and one lineage of the cosmopolitan genotype were observed: Lineage 1, Asian-American genotype (connection to Puerto Rico); Lineage 5, cosmopolitan genotype (connection to Peru). Our results provide important data regarding the study of DENV genotypes and lineage distribution and open up possibilities for probable introduction and dissemination routes.

Funder

Coordination for the Improvement of Higher Education Personnel

PROPESP/UFPA

Publisher

MDPI AG

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Immunology and Microbiology

Link

https://www.mdpi.com/2414-6366/9/1/17/pdf

Reference56 articles.

1. Lessa, C.L.S., Hodel, K.V.S., Gonçalves, M.S., and Machado, B.A.S. (2023). Dengue as a Disease Threatening Global Health: A Narrative Review Focusing on Latin America and Brazil. Trop. Med. Infect. Dis., 8.

2. Renaming of the genus Flavivirus to Orthoflavivirus and extension of binomial species names within the family Flaviviridae;Postler;Arch. Virol.,2023

3. Research on Dengue during World War II;Sabin;Am. J. Trop. Med. Hyg.,1952

4. Dengue: A continuing global threat;Halstead;Nat. Rev. Microbiol.,2010

5. World Health Organization-WHO (2000). Dengue and Dengue haemorhagic fever, WHO Report on Global Surveillance of Epidemic-Prone Infectious Disease.