Comparison of 116 Radiosurgery Treatment Plans for Multi-Leaf and Cone Collimator on a Varian Edge Linac: Are Cones Superior in the Daily Routine?

Author:

Čehobašić Adlan12ORCID,Paladino Josip1,Kaučić Hrvoje1ORCID,Mišir-Krpan Ana13,Leipold Vanda12ORCID,Mlinarić Mihaela1ORCID,Kosmina Domagoj1,Mack Andreas4,Schwarz Dragan156,Divošević Sunčana1,Alerić Ivana1ORCID

Affiliation:

1. Specijalna Bolnica Radiochirurgia Zagreb, Ulica Dr. Franje Tuđmana 4, 10431 Sveta Nedelja, Croatia

2. Medicinski Fakultet Osijek, Sveučilište Josipa Jurja Strossmayera u Osijeku, Josipa Huttlera 4, 31000 Osijek, Croatia

3. Medicinski Fakultet, Sveučilište u Zagrebu, Šalata 3, 10000 Zagreb, Croatia

4. Swiss NeuroRadiosurgery Center, Bürglistrasse 29, 8002 Zürich, Switzerland

5. Medicinski Fakultet, Sveučilišta u Rijeci, Braće Branchetta 20/1, 51000 Rijeka, Croatia

6. Fakultet za Dentalnu Medicinu i Zdravstvo Osijek, Sveučilište Josipa Jurja Strossmayera u Osijeku, Crkvena Ulica 21, 31000 Osijek, Croatia

Abstract

Delivering focused radiation doses via linear accelerators is a crucial component of stereotactic radiosurgery (SRS) for brain metastases. The Varian Edge linear accelerator provides highly conformal radiation therapy through a high-definition multi-leaf collimator (HD120 MLC) and conical collimator (CC). HD120 MLC adapts to the shape of the target volume using movable tungsten leaves, while CC has a block of conical shape (cones). CC in SRS treatments of small brain metastases is preferred due to its mechanical stability and steeper dose fall-off, potentially sparing organs at risk (OARs) and the brain better than HD120 MLC. This study aims to determine if CC offers significant advantages over HD120 MLC for SRS treatments. For 116 metastatic lesions, CC and HD120 MLC treatment plans were created in Varian Eclipse TPS and compared based on various dose parameters, robustness tests, and QA measurements. The results indicate that CC provides no significant advantages over HD120 MLC, except for slight, clinically insignificant benefits in brain sparing and dose fall-off for the smallest lesions. HD120 MLC outperforms CC in almost every aspect, making it a better choice for irradiating brain metastases with 0.1 cm3 or higher volumes.

Publisher

MDPI AG

Subject

Paleontology,Space and Planetary Science,General Biochemistry, Genetics and Molecular Biology,Ecology, Evolution, Behavior and Systematics

Reference40 articles.

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5. Harris, L., and Das, J.M. (2023, March 11). Stereotactic Radiosurgery, Available online: https://www.ncbi.nlm.nih.gov/books/NBK542166/.

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