Comprehensive Insights into Chondroblastoma Metastasis: Metastatic Patterns and Therapeutic Approaches

Author:

Samargandi Ramy12ORCID,Bafail Abrar3,Le Nail Louis-Romée1,Berhouet Julien1ORCID

Affiliation:

1. Service de Chirurgie Orthopédique et Traumatologique, Centre Hospitalier Régional Universitaire (CHRU) de Tours, 1C Avenue de la République, 37170 Chambray-les-Tours, France

2. Department of Orthopedic Surgery, Faculty of Medicine, University of Jeddah, Jeddah 23218, Saudi Arabia

3. Service de Médecine Nucléaire, Centre Hospitalier Régional Universitaire (CHRU) de Tours, 1C Avenue de la République, 37170 Chambray-les-Tours, France

Abstract

Chondroblastoma metastasis, though rare, represents a clinically significant and notably important aspect of bone tumors. Understanding its epidemiological characteristics, pathological features, and treatment modalities, despite its infrequency, is imperative for comprehensive patient management. This review aims to elucidate the epidemiology, molecular mechanisms, diagnostic challenges, and therapeutic strategies associated with chondroblastoma metastasis. The patterns, prognostic factors, and treatment outcomes were explored through an analysis of case studies and clinical reports. Notably, we highlighted emerging therapeutic perspectives aimed at improving patient outcomes. To the best of our knowledge, there has been no previous review addressing these matters cumulatively, highlighting a significant gap in the existing scholarly literature. By shedding light on the nuances of chondroblastoma metastasis, this review contributes to the advancement of knowledge in this field and informs clinical decision-making for improved patient care.

Publisher

MDPI AG

Reference102 articles.

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3. Cytological diagnosis of chondroblastoma: Diagnostic challenge for the cytopathologist;Akhtar;BMJ Case Rep.,2014

4. Heymann, D. (2010). Chapter 19—Recent Advances in the Biology of Bone Tumors and New Diagnostic Tools. Bone Cancer, Academic Press.

5. Harish, K., Janaki, M.G., and Alva, N.K. (2004). “Primary” aggressive chondroblastoma of the humerus: A case report. BMC Musculoskelet. Disord., 5.

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